Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

7q32.3

lncRNA

LINC-PINT ( ENSG00000231721)

miRNA

hsa-miR-665 (MIMAT0004952)

mRNA

CD274 (ENSG00000120217)

Disease

TGCT

FDR

5.34E-5

Reported as biomarkers
3

Circulating
1

Drug resistent
2

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' uccccGGAGUCGGAGGACCa 5' hsa-miR-665
               |||| ||||||||| 
target 5' tgcaaCCTCTGCCTCCTGGg 3' LINC-PINT
Start: 1713  End: 1732
Energy: -29.64 kcal/mol
Align Score: 167
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3' U             A     A  A 5' hsa-miR-665
           CCCC GGAGUCGG    GG CC    
           GGGG CCUUGGCC    CC GG    
target 5' C    U        CUGG  G  G 3' LINC-PINT
Start: 105  End: 125
Energy: -33.1 kcal/mol
Align Score: 0.003131
miRNA  3' U             A     A  A 5' hsa-miR-665
           CCCC GGAGUCGG    GG CC    
           GGGG CCUUGGCC    CC GG    
target 5' C    U        CUGG  G  G 3' LINC-PINT
Start: 21  End: 41
Energy: -33.1 kcal/mol
Align Score: 0.004411
miRNA  3' U             A     A  A 5' hsa-miR-665
           CCCC GGAGUCGG    GG CC    
           GGGG CCUUGGCC    CC GG    
target 5' C    U        CUGG  G  G 3' LINC-PINT
Start: 141  End: 161
Energy: -33.1 kcal/mol
Align Score: 0.002788
miRNA  3 U             A     A  A 5 hsa-miR-665
           CCCC GGAGUCGG    GG CC    
           GGGG CCUUGGCC    CC GG    
target 5 C    U        CUGG  G  G 3 LINC-PINT
Start: 105  End: 125
Energy: -33.1 kcal/mol
Align Score: 0.003131
miRNA  3 U             A     A  A 5 hsa-miR-665
           CCCC GGAGUCGG    GG CC    
           GGGG CCUUGGCC    CC GG    
target 5 C    U        CUGG  G  G 3 LINC-PINT
Start: 21  End: 41
Energy: -33.1 kcal/mol
Align Score: 0.004411

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC-PINT

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-665

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CD274

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 7q32.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.