Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q31.2

lncRNA

TTN-AS1 ( ENSG00000237298)

miRNA

hsa-miR-1254 (MIMAT0005905)

mRNA

CCAR1 (ENSG00000060339)

Disease

THYM

FDR

4.85E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 UGA        G           AAG        5 hsa-miR-1254
             CGUCCGAG         UCG   GUCCGA    
             GUAGGCUC         AGC   CAGGCU    
target 5   G        ACCCGUGAA   A        A 3 TTN-AS1
Start: 439  End: 459
Energy: -32.4 kcal/mol
Align Score: 0.004847
miRNA  3 U                          AA   U      5 hsa-miR-1254
           GACGUCCG            AGGUCG   GG CCGA    
           UUGCAGGC            UCCAGU   UC GGCU    
target 5 U        CUCGAGAACAUA      GAG       A 3 TTN-AS1
Start: 667  End: 687
Energy: -32.7 kcal/mol
Align Score: 0.006877
miRNA  3 UG  GU           G            A 5 hsa-miR-1254
            AC  CCGAGG   UC AAG    GUCCG    
            UG  GGCUUC   AG UUC    CAGGC    
target 5  A  GU      UUG  G   UCCA     A 3 TTN-AS1
Start: 416  End: 436
Energy: -31.3 kcal/mol
Align Score: 0.007789
miRNA  3 U                      U         GA 5 hsa-miR-1254
           GACG           UCCGAGG CGAAGGUCC     
           CUGC           AGGCUCU GCUUUUAGG     
target 5 C    CUCUCAUUUUA                 G  3 TTN-AS1
Start: 63  End: 83
Energy: -32.6 kcal/mol
Align Score: 0.002695
miRNA  3 U  C        U         GA 5 hsa-miR-1254
           GA GUCCGAGG CGAAGGUCC     
           CU CAGGCUCU GCUUUUAGG     
target 5 U                     G  3 TTN-AS1
Start: 178  End: 198
Energy: -32.6 kcal/mol
Align Score: 0.004498

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for TTN-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1254

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CCAR1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q31.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.