Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

7q35

lncRNA

OR2A1-AS1 ( ENSG00000244479)

miRNA

hsa-miR-128-1-5p (MIMAT0026477)

mRNA

BMI1 (ENSG00000168283)

Disease

THYM

FDR

3.98E-2

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' agAGUCUGUCACGAUGCCGGGGc 5' hsa-miR-128-1-5p
            ||| |:: |||| ||||||| 
target 5' tgTCACATGCTGCTTCGGCCCCa 3' OR2A1-AS1
Start: 37  End: 59
Energy: -25.57 kcal/mol
Align Score: 173
miRNA  3' agAGUCUGUCACGAUGCCGGGGc 5' hsa-miR-128-1-5p
            ||| |:: |||| ||||||| 
target 5' tgTCACATGCTGCTTCGGCCCCa 3' OR2A1-AS1
Start: 215  End: 237
Energy: -25.57 kcal/mol
Align Score: 173
miRNA  3' agAGUCUGUCACGAUGCCGGGGc 5' hsa-miR-128-1-5p
            ||| |:: |||| ||||||| 
target 5' tgTCACATGCTGCTTCGGCCCCa 3' OR2A1-AS1
Start: 108  End: 130
Energy: -25.57 kcal/mol
Align Score: 173
miRNA  3' agAGUCUGUCACGAUGCCGGGGc 5' hsa-miR-128-1-5p
            ||| |:: |||| ||||||| 
target 5' tgTCACATGCTGCTTCGGCCCCa 3' OR2A1-AS1
Start: 28  End: 50
Energy: -25.57 kcal/mol
Align Score: 173
miRNA  3' agAGUCUGUCACGAUGCCGGGGc 5' hsa-miR-128-1-5p
            ||| |:: |||| ||||||| 
target 5' tgTCACATGCTGCTTCGGCCCCa 3' OR2A1-AS1
Start: 193  End: 215
Energy: -25.57 kcal/mol
Align Score: 173
TargetScan target site prediction
miRNA  3' AGAGUCUGUCACGAUGCCGGGGC 5' hsa-miR-128-1-5p
                         ||||||| 
target 5' UGUCACAUGCUGCUUCGGCCCCA OR2A1-AS1
Start: 52  End: 59
Site type: 8mer-1a
Context++ Score: -0.514
miRNA  3' AGAGUCUGUCACGAUGCCGGGGC 5' hsa-miR-128-1-5p
                         ||||||| 
target 5' UGUCACAUGCUGCUUCGGCCCCA OR2A1-AS1
Start: 230  End: 237
Site type: 8mer-1a
Context++ Score: -0.469
miRNA  3' AGAGUCUGUCACGAUGCCGGGGC 5' hsa-miR-128-1-5p
                         ||||||| 
target 5' UGUCACAUGCUGCUUCGGCCCCA OR2A1-AS1
Start: 123  End: 130
Site type: 8mer-1a
Context++ Score: -0.496
miRNA  3' AGAGUCUGUCACGAUGCCGGGGC 5' hsa-miR-128-1-5p
                         ||||||| 
target 5' UGUCACAUGCUGCUUCGGCCCCA OR2A1-AS1
Start: 43  End: 50
Site type: 8mer-1a
Context++ Score: -0.516
miRNA  3' AGAGUCUGUCACGAUGCCGGGGC 5' hsa-miR-128-1-5p
                         ||||||| 
target 5' UGUCACAUGCUGCUUCGGCCCCA OR2A1-AS1
Start: 208  End: 215
Site type: 8mer-1a
Context++ Score: -0.475
RNAbybrid target site prediction
miRNA  3' AG                  U       C 5' hsa-miR-128-1-5p
            AGUC    UGU C ACGA GCCGGGG    
            UCGG    ACA G UGCU CGGCCCC    
target 5'  G    UGUC   U C    U       A 3' OR2A1-AS1
Start: 32  End: 52
Energy: -31.8 kcal/mol
Align Score: 0.009149
miRNA  3' AG                  U       C 5' hsa-miR-128-1-5p
            AGUC    UGU C ACGA GCCGGGG    
            UCGG    ACA G UGCU CGGCCCC    
target 5'  G    UGUC   U C    U       A 3' OR2A1-AS1
Start: 210  End: 230
Energy: -31.8 kcal/mol
Align Score: 0.005577
miRNA  3' AG                  U       C 5' hsa-miR-128-1-5p
            AGUC    UGU C ACGA GCCGGGG    
            UCGG    ACA G UGCU CGGCCCC    
target 5'  G    UGUC   U C    U       A 3' OR2A1-AS1
Start: 103  End: 123
Energy: -31.8 kcal/mol
Align Score: 0.004202
miRNA  3' AG                  U       C 5' hsa-miR-128-1-5p
            AGUC    UGU C ACGA GCCGGGG    
            UCGG    ACA G UGCU CGGCCCC    
target 5'  G    UGUC   U C    U       A 3' OR2A1-AS1
Start: 23  End: 43
Energy: -31.8 kcal/mol
Align Score: 0.005063
miRNA  3' AG                  U       C 5' hsa-miR-128-1-5p
            AGUC    UGU C ACGA GCCGGGG    
            UCGG    ACA G UGCU CGGCCCC    
target 5'  G    UGUC   U C    U       A 3' OR2A1-AS1
Start: 188  End: 208
Energy: -31.8 kcal/mol
Align Score: 0.008598

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for OR2A1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-128-1-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for BMI1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 7q35

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.