Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.23

lncRNA

SVIL-AS1 ( ENSG00000224597)

miRNA

hsa-miR-149-3p (MIMAT0004609)

mRNA

GPC1 (ENSG00000063660)

Disease

THYM

FDR

2.08E-2

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3                C            5 hsa-miR-149-3p
           CGUG   UCGGGGG  AGGGAGGGA    
           GCAC   GGCUCCU  UCCCUCCUU    
target 5 A    ACA       UU         C 3 SVIL-AS1
Start: 607  End: 627
Energy: -35 kcal/mol
Align Score: 0.0022
miRNA  3 CG          CA           A      5 hsa-miR-149-3p
            UGUCGG GGG          GGG GGGA    
            GCAGCC CCC          CCC CCCU    
target 5  U      A   CUUAGAGCAA        U 3 SVIL-AS1
Start: 186  End: 206
Energy: -30.1 kcal/mol
Align Score: 0.008139
miRNA  3 C     GG          G   GA 5 hsa-miR-149-3p
           GUGUC     GGGCAGG AGG     
           CACAG     CCUGUCC UCC     
target 5 A     AUGAA       A   A  3 SVIL-AS1
Start: 379  End: 399
Energy: -29.5 kcal/mol
Align Score: 0.007638
miRNA  3 C     G      G  A   A 5 hsa-miR-149-3p
           GUGUC GGGGCA GG GGG    
           CACAG CCCUGU CC CCU    
target 5 A            G  A   G 3 SVIL-AS1
Start: 529  End: 549
Energy: -30.9 kcal/mol
Align Score: 0.008189
miRNA  3 C                         A 5 hsa-miR-149-3p
           GUG  UCGGGGG CAGGGA   GGG    
           CAC  AGUCCCC GUUCCU   UCC    
target 5 C   CA       A      AAC   A 3 SVIL-AS1
Start: 315  End: 335
Energy: -30.7 kcal/mol
Align Score: 0.005996

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SVIL-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-149-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for GPC1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.23

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.