Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

19q11

lncRNA

CTC-459F4.3 ( ENSG00000267575)

miRNA

hsa-miR-149-3p (MIMAT0004609)

mRNA

E2F1 (ENSG00000101412)

Disease

THYM

FDR

3.58E-2

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 C UG       C        A 5 hsa-miR-149-3p
           G  UCGGGGG AGGGAGGG    
           C  AGCCUCU UCCCUCCU    
target 5 A UG                G 3 CTC-459F4.3
Start: 217  End: 237
Energy: -35.2 kcal/mol
Align Score: 0.001649
miRNA  3             G A              A 5 hsa-miR-149-3p
           CG UGUCGGGG C        GGGAGGG    
           GC ACAGCUCU G        CUCUCCC    
target 5 U  U        G AGACAGAG       A 3 CTC-459F4.3
Start: 220  End: 240
Energy: -31.4 kcal/mol
Align Score: 0.006845
miRNA  3                       G                  A 5 hsa-miR-149-3p
           CGUG           UCGGGG     CAGGG     AGGG    
           GCAC           GGCCCC     GUCCC     UCCC    
target 5 A    GGGGCCUGUGG      GGUAA     GGUGU    G 3 CTC-459F4.3
Start: 342  End: 362
Energy: -34.3 kcal/mol
Align Score: 0.005636
miRNA  3             G A              A 5 hsa-miR-149-3p
           CG UGUCGGGG C        GGGAGGG    
           GC ACAGCUCU G        CUCUCCC    
target 5 U  U        G AGACAGAG       A 3 CTC-459F4.3
Start: 249  End: 269
Energy: -31.4 kcal/mol
Align Score: 0.008245
miRNA  3               C    A   A 5 hsa-miR-149-3p
           CGUG  UCGGGGG AGGG GGG    
           GCAU  AGCCUCC UCCC CCC    
target 5 A    CA            G   A 3 CTC-459F4.3
Start: 165  End: 185
Energy: -35.4 kcal/mol
Align Score: 0.000835

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for CTC-459F4.3

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-149-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for E2F1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 19q11

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.