Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

6p22.1

lncRNA

HCG18 ( ENSG00000231074)

miRNA

hsa-miR-1291 (MIMAT0005881)

mRNA

ERN1 (ENSG00000178607)

Disease

ESCA

FDR

2.25E-9

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3           A  A      G           5 hsa-miR-1291
           UGAC GACC GA   GUCA   UCCCGGU    
           ACUG CUGG CU   CAGU   GGGGCUA    
target 5 C    U    C  GGG    GGA       G 3 HCG18
Start: 247  End: 267
Energy: -35.3 kcal/mol
Align Score: 0.007247
miRNA  3                        CAG              U 5 hsa-miR-1291
           UGACG               AC   AAG UCAGUCCCGG    
           ACUGU               UG   UUC AGUCAGGGCC    
target 5 U     GUGCAGAAAUGUGAU  AGA   A          U 3 HCG18
Start: 220  End: 240
Energy: -31.3 kcal/mol
Align Score: 0.007197
miRNA  3                        CAG              U 5 hsa-miR-1291
           UGACG               AC   AAG UCAGUCCCGG    
           ACUGU               UG   UUC AGUCAGGGCC    
target 5 U     GUGCAGAAAUGUGAU  AGA   A          U 3 HCG18
Start: 108  End: 128
Energy: -31.3 kcal/mol
Align Score: 0.004132
miRNA  3 UGA  A    AA            U 5 hsa-miR-1291
             CG CCAG  GUCAGU CCCGG    
             GC GGUU  CAGUCA GGGCC    
target 5   A  A    GC      U     C 3 HCG18
Start: 807  End: 827
Energy: -33.7 kcal/mol
Align Score: 0.005222
miRNA  3          A     G      G   CGGU 5 hsa-miR-1291
           UGACGACC   GAA    UCA UCC       
           GCUGCUGG   CUU    GGU AGG       
target 5 U        AAG   AGCA   G   A    3 HCG18
Start: 110  End: 130
Energy: -29.2 kcal/mol
Align Score: 0.007853

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for HCG18

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1291

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ERN1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 6p22.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.