Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p22.1

lncRNA

SLC8A1-AS1 ( ENSG00000227028)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

FOXM1 (ENSG00000111206)

Disease

THYM

FDR

1.75E-10

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'    UGGUCCAAGGUGGGGUCGUCCG 5' hsa-miR-370-3p
                   |||||   ||||||| 
target 5' GAAGCUGGAUUCCAU--CAGCAGGA SLC8A1-AS1
Start: 654  End: 661
Site type: 8mer-1a
Context++ Score: -0.453
miRNA  3'    UGGUCCAAGGUGGGGUCGUCCG 5' hsa-miR-370-3p
                   |||||   ||||||| 
target 5' GAAGCUGGAUUCCAU--CAGCAGGA SLC8A1-AS1
Start: 214  End: 221
Site type: 8mer-1a
Context++ Score: -0.466
miRNA  3'    UGGUCCAAGGUGGGGUCGUCCG 5' hsa-miR-370-3p
                   |||||   ||||||| 
target 5' GAAGCUGGAUUCCAU--CAGCAGGA SLC8A1-AS1
Start: 654  End: 661
Site type: 8mer-1a
Context++ Score: -0.453
miRNA  3'    UGGUCCAAGGUGGGGUCGUCCG 5' hsa-miR-370-3p
                   |||||   ||||||| 
target 5' GAAGCUGGAUUCCAU--CAGCAGGA SLC8A1-AS1
Start: 214  End: 221
Site type: 8mer-1a
Context++ Score: -0.466
RNAbybrid target site prediction
miRNA  3' U     A     GG      U      5' hsa-miR-370-3p
           GGUCC  AGGU   GGUCG  CCG    
           UCAGG  UUCG   CUAGC  GGC    
target 5' G     AG    AGA     CU   C 3' SLC8A1-AS1
Start: 45  End: 65
Energy: -26 kcal/mol
Align Score: 0.008152
miRNA  3' U       AA  U        C     5' hsa-miR-370-3p
           GG  UCC  GG GGGGUCGU  CG    
           CC  AGG  CC CCCCAGCA  GC    
target 5' U  UG       U        AU  A 3' SLC8A1-AS1
Start: 72  End: 92
Energy: -28.1 kcal/mol
Align Score: 0.006641
miRNA  3' U       AA  U        C     5' hsa-miR-370-3p
           GG  UCC  GG GGGGUCGU  CG    
           CC  AGG  CC CCCCAGCA  GC    
target 5' U  UG       U        AU  A 3' SLC8A1-AS1
Start: 69  End: 89
Energy: -28.1 kcal/mol
Align Score: 0.005631
miRNA  3' U       AA  U        C     5' hsa-miR-370-3p
           GG  UCC  GG GGGGUCGU  CG    
           CC  AGG  CC CCCCAGCA  GC    
target 5' U  UG       U        AU  A 3' SLC8A1-AS1
Start: 18  End: 38
Energy: -28.1 kcal/mol
Align Score: 0.006113
miRNA  3'                           GU        5' hsa-miR-370-3p
           UGGUCC           AAGGUGGG  CGUCCG    
           ACCAGG           UUCCAUUC  GCAGGU    
target 5' U      CAUUUAAAAUC                A 3' SLC8A1-AS1
Start: 480  End: 500
Energy: -31.6 kcal/mol
Align Score: 0.006488

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SLC8A1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for FOXM1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p22.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.