Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

20q11.23

lncRNA

SNHG17 ( ENSG00000196756)

miRNA

hsa-miR-4649-3p (MIMAT0019712)

mRNA

PTPN6 (ENSG00000111679)

Disease

THYM

FDR

8.15E-7

Reported as biomarkers
0

Circulating
0

Drug resistent
1

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 AC      CC                5 hsa-miR-4649-3p
            CCCUCU   GUC  CGGAGUCU    
            GGGAGA   CAG  GCCUCAGA    
target 5  U      CUU   CU        G 3 SNHG17
Start: 353  End: 373
Energy: -31.5 kcal/mol
Align Score: 0.004877
miRNA  3 AC      CC                5 hsa-miR-4649-3p
            CCCUCU   GUC  CGGAGUCU    
            GGGAGA   CAG  GCCUCAGA    
target 5  U      CUU   CU        G 3 SNHG17
Start: 721  End: 741
Energy: -31.5 kcal/mol
Align Score: 0.009372
miRNA  3 A     C    U    AG     5 hsa-miR-4649-3p
           CCCCU UCCG CCGG  UCU    
           GGGGA AGGC GGCC  AGA    
target 5 C               AG   G 3 SNHG17
Start: 219  End: 239
Energy: -34.3 kcal/mol
Align Score: 0.002276
miRNA  3 A     C    U    AG     5 hsa-miR-4649-3p
           CCCCU UCCG CCGG  UCU    
           GGGGA AGGC GGCC  AGA    
target 5 C               AG   G 3 SNHG17
Start: 199  End: 219
Energy: -34.3 kcal/mol
Align Score: 0.001799
miRNA  3 A     C    U    AG     5 hsa-miR-4649-3p
           CCCCU UCCG CCGG  UCU    
           GGGGA AGGC GGCC  AGA    
target 5 C               AG   G 3 SNHG17
Start: 200  End: 220
Energy: -34.3 kcal/mol
Align Score: 0.002832

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SNHG17

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-4649-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for PTPN6

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 20q11.23

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.