Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

5q35.3

lncRNA

PRR7-AS1 ( ENSG00000246334)

miRNA

hsa-miR-149-3p (MIMAT0004609)

mRNA

MYBL2 (ENSG00000101057)

Disease

ESCA

FDR

1.26E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3              C             A 5 hsa-miR-149-3p
           CGU GUCGGGGG AG     GGAGGG    
           GCA UAGCCCCC UC     CCUCCC    
target 5 G   G           ACUGG      C 3 PRR7-AS1
Start: 484  End: 504
Energy: -34.9 kcal/mol
Align Score: 0.00218
miRNA  3    UG         C        A 5 hsa-miR-149-3p
           CG    UCGGGGG AGGGAGGG    
           GC    AGUCCCC UUCCUCCC    
target 5 A  UUUA       C        A 3 PRR7-AS1
Start: 177  End: 197
Energy: -36.1 kcal/mol
Align Score: 0.000897
miRNA  3 C          CA           5 hsa-miR-149-3p
           GUGUCGGGGG  GGGA GGGA    
           CACAGCUCCC  CCCU CUCU    
target 5 A          A     A    U 3 PRR7-AS1
Start: 296  End: 316
Energy: -33.9 kcal/mol
Align Score: 0.001863
miRNA  3 C         G              G      A 5 hsa-miR-149-3p
           GUGUCGGGG C            A GGAGGG    
           CACAGCCCU G            U CCUCCC    
target 5 C         G CCUCCGUGGACA G      C 3 PRR7-AS1
Start: 124  End: 144
Energy: -33.6 kcal/mol
Align Score: 0.001628

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PRR7-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-149-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for MYBL2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 5q35.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.