Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

19q11

lncRNA

CTC-459F4.3 ( ENSG00000267575)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

MGMT (ENSG00000170430)

Disease

BLCA

FDR

3.51E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3     U       G   U                 5 hsa-miR-370-3p
           UGG CCAAGGU GGG CG         UCCG    
           GCC GGUUCCA CCC GC         GGGC    
target 5 U   U       G   U  UUCAGCACG    C 3 CTC-459F4.3
Start: 320  End: 340
Energy: -36.6 kcal/mol
Align Score: 0.002681
miRNA  3     UCCA   U       G      5 hsa-miR-370-3p
           UGG    AGG G GGGUC UCCG    
           GCC    UCC C CCCAG GGGC    
target 5 A   UCC      G     G    C 3 CTC-459F4.3
Start: 172  End: 192
Energy: -29.7 kcal/mol
Align Score: 0.008238
miRNA  3 UGGU       G                  5 hsa-miR-370-3p
              CCAAGGU GG  GUCG    UCCG    
              GGUUCCA CC  UAGU    GGGC    
target 5    C       G  GU    CACA    G 3 CTC-459F4.3
Start: 11  End: 31
Energy: -29.7 kcal/mol
Align Score: 0.009561
miRNA  3 U     A              GG          5 hsa-miR-370-3p
           GGUCC      AGG   UGG  UC GUCCG    
           CCAGG      UCC   GCC  GG CAGGC    
target 5 U     CAUGUG   UGA   AG  A     U 3 CTC-459F4.3
Start: 410  End: 430
Energy: -30 kcal/mol
Align Score: 0.009651

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for CTC-459F4.3

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for MGMT

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 19q11

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.