Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10q22.2

lncRNA

ZNF503-AS2 ( ENSG00000237149)

miRNA

hsa-miR-128-1-5p (MIMAT0026477)

mRNA

BMI1 (ENSG00000168283)

Disease

BRCA

FDR

2.01E-9

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3' AGAGUCUGUCACGAUGCCGGGGC 5' hsa-miR-128-1-5p
                         ||||||| 
target 5' UUCAAUGCAACUCCUCGGCCCCA ZNF503-AS2
Start: 1275  End: 1282
Site type: 8mer-1a
Context++ Score: -0.538
miRNA  3' AGAGUCUGUCACGAUGCCGGGGC 5' hsa-miR-128-1-5p
                         ||||||| 
target 5' UUCAAUGCAACUCCUCGGCCCCA ZNF503-AS2
Start: 834  End: 841
Site type: 8mer-1a
Context++ Score: -0.533
miRNA  3' AGAGUCUGUCACGAUGCCGGGGC 5' hsa-miR-128-1-5p
                         ||||||| 
target 5' UUCAAUGCAACUCCUCGGCCCCA ZNF503-AS2
Start: 603  End: 610
Site type: 8mer-1a
Context++ Score: -0.445
miRNA  3' AGAGUCUGUCACGAUGCCGGGGC 5' hsa-miR-128-1-5p
                         ||||||| 
target 5' UUCAAUGCAACUCCUCGGCCCCA ZNF503-AS2
Start: 1275  End: 1282
Site type: 8mer-1a
Context++ Score: -0.538
miRNA  3' AGAGUCUGUCACGAUGCCGGGGC 5' hsa-miR-128-1-5p
                         ||||||| 
target 5' UUCAAUGCAACUCCUCGGCCCCA ZNF503-AS2
Start: 834  End: 841
Site type: 8mer-1a
Context++ Score: -0.533
RNAbybrid target site prediction
miRNA  3'                     A    C     C 5' hsa-miR-128-1-5p
           AGAGU      CUGUCACG   UG CGGGG    
           UCUCG      GGCAGUGC   GC GCCCC    
target 5' C     CUGCCU        CUG  A     C 3' ZNF503-AS2
Start: 952  End: 972
Energy: -35.3 kcal/mol
Align Score: 0.004806
miRNA  3'                     A    C     C 5' hsa-miR-128-1-5p
           AGAGU      CUGUCACG   UG CGGGG    
           UCUCG      GGCAGUGC   GC GCCCC    
target 5' C     CUGCCU        CUG  A     C 3' ZNF503-AS2
Start: 396  End: 416
Energy: -35.3 kcal/mol
Align Score: 0.001699
miRNA  3'                     A    C     C 5' hsa-miR-128-1-5p
           AGAGU      CUGUCACG   UG CGGGG    
           UCUCG      GGCAGUGC   GC GCCCC    
target 5' C     CUGCCU        CUG  A     C 3' ZNF503-AS2
Start: 511  End: 531
Energy: -35.3 kcal/mol
Align Score: 0.003147
miRNA  3'                     A    C     C 5' hsa-miR-128-1-5p
           AGAGU      CUGUCACG   UG CGGGG    
           UCUCG      GGCAGUGC   GC GCCCC    
target 5' C     CUGCCU        CUG  A     C 3' ZNF503-AS2
Start: 280  End: 300
Energy: -35.3 kcal/mol
Align Score: 0.003612
miRNA  3'                     A    C     C 5' hsa-miR-128-1-5p
           AGAGU      CUGUCACG   UG CGGGG    
           UCUCG      GGCAGUGC   GC GCCCC    
target 5' C     CUGCCU        CUG  A     C 3' ZNF503-AS2
Start: 329  End: 349
Energy: -35.3 kcal/mol
Align Score: 0.001449

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZNF503-AS2

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-128-1-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for BMI1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10q22.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.