Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

12q24.22

lncRNA

LINC00173 ( ENSG00000196668)

miRNA

hsa-miR-149-3p (MIMAT0004609)

mRNA

AKT1 (ENSG00000142208)

Disease

BRCA

FDR

5.78E-131

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3    U                   A       A 5 hsa-miR-149-3p
           CG GUCG          GGGGC GGGAGGG    
           GC CAGC          CCCCG CCCUCCC    
target 5 C  U    GGAUUCCCUC     C       C 3 LINC00173
Start: 401  End: 421
Energy: -37.4 kcal/mol
Align Score: 0.002397
miRNA  3 C                  A      5 hsa-miR-149-3p
           GUGUCGGGGG   CAGGG GGGA    
           CGCAGCCCUC   GUCCC CCUU    
target 5 A          CUU          C 3 LINC00173
Start: 118  End: 138
Energy: -36.1 kcal/mol
Align Score: 0.000641
miRNA  3    U                   A       A 5 hsa-miR-149-3p
           CG GUCG          GGGGC GGGAGGG    
           GC CAGC          CCCCG CCCUCCC    
target 5 C  U    GGAUUCCCUC     C       C 3 LINC00173
Start: 509  End: 529
Energy: -37.4 kcal/mol
Align Score: 0.000546
miRNA  3 CGUG            G   G     5 hsa-miR-149-3p
              UCGG GGG  CA GGA GGA    
              GGCC CCC  GU CCU CCU    
target 5    G    A   AU  G   G   G 3 LINC00173
Start: 228  End: 248
Energy: -28.2 kcal/mol
Align Score: 0.009356

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC00173

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-149-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for AKT1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 12q24.22

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.