Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

1p36.33

lncRNA

RP11-54O7.3 ( ENSG00000223764)

miRNA

hsa-miR-185-3p (MIMAT0004611)

mRNA

AKT1 (ENSG00000142208)

Disease

BRCA

FDR

5.81E-19

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' cugGUCUCCUUUCGGUCGGGGa 5' hsa-miR-185-3p
             |||: |::| :||||||| 
target 5' cggCAGGAGGGACTCAGCCCCt 3' RP11-54O7.3
Start: 3318  End: 3339
Energy: -31.95 kcal/mol
Align Score: 163
miRNA  3' cugGUCUCCUUUCGGUCGGGGa 5' hsa-miR-185-3p
             |||: |::| :||||||| 
target 5' cggCAGGAGGGACTCAGCCCCt 3' RP11-54O7.3
Start: 560  End: 581
Energy: -31.95 kcal/mol
Align Score: 163
TargetScan target site prediction
miRNA  3'  CUGGUCUCCUUUCGGUCGGGGA 5' hsa-miR-185-3p
             |||||       ||||||| 
target 5' AGCCCAGAUGUGGUACAGCCCCA RP11-54O7.3
Start: 35  End: 42
Site type: 8mer-1a
Context++ Score: -0.467
miRNA  3'  CUGGUCUCCUUUCGGUCGGGGA 5' hsa-miR-185-3p
             |||||       ||||||| 
target 5' AGCCCAGAUGUGGUACAGCCCCA RP11-54O7.3
Start: 35  End: 42
Site type: 8mer-1a
Context++ Score: -0.467
RNAbybrid target site prediction
miRNA  3'    G                        5' hsa-miR-185-3p
           CU GUC UCCUUUC G GUCGGGGA    
           GG CGG AGGAGGG C CAGCCCCU    
target 5' C  G   C       A U        C 3' RP11-54O7.3
Start: 556  End: 576
Energy: -34.6 kcal/mol
Align Score: 0.005614
miRNA  3' C       CU              GA 5' hsa-miR-185-3p
           UGGUCUC     UUCGG UCGGG     
           GCCAGAG     GGGCC AGCCC     
target 5' A       CCCCU     C     A  3' RP11-54O7.3
Start: 600  End: 620
Energy: -33.2 kcal/mol
Align Score: 0.003521
miRNA  3    G                        5 hsa-miR-185-3p
           CU GUC UCCUUUC G GUCGGGGA    
           GG CGG AGGAGGG C CAGCCCCU    
target 5 C  G   C       A U        C 3 RP11-54O7.3
Start: 556  End: 576
Energy: -34.6 kcal/mol
Align Score: 0.005614
miRNA  3 C       CU              GA 5 hsa-miR-185-3p
           UGGUCUC     UUCGG UCGGG     
           GCCAGAG     GGGCC AGCCC     
target 5 A       CCCCU     C     A  3 RP11-54O7.3
Start: 600  End: 620
Energy: -33.2 kcal/mol
Align Score: 0.003521

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for RP11-54O7.3

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-185-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for AKT1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 1p36.33

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.