Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

12q24.23

lncRNA

PXN-AS1 ( ENSG00000255857)

miRNA

hsa-miR-296-3p (MIMAT0004679)

mRNA

CX3CR1 (ENSG00000168329)

Disease

BRCA

FDR

6.32E-20

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 CCUC       UG G         5 hsa-miR-296-3p
              UCGGAGG  G UUGGGAG    
              GGCCUCC  C AAUCCUC    
target 5    U       UG         C 3 PXN-AS1
Start: 743  End: 763
Energy: -31.8 kcal/mol
Align Score: 0.008572
miRNA  3 CC      A                      AG 5 hsa-miR-296-3p
            UCUCGG GGU           GGGUUGGG     
            AGGGCC CCA           CCCAGCCU     
target 5  C          UCCCGCUGCUC        G  3 PXN-AS1
Start: 393  End: 413
Energy: -30.8 kcal/mol
Align Score: 0.009895
miRNA  3 CCUCU      U               5 hsa-miR-296-3p
               CGGAGG    GGGUUGGGAG    
               GCUUCC    CCCAACCCUC    
target 5     U      CCAC          A 3 PXN-AS1
Start: 731  End: 751
Energy: -34.9 kcal/mol
Align Score: 0.002678
miRNA  3 CCU     A                         5 hsa-miR-296-3p
             CUCGG   GGUGGGU       UG GGAG    
             GAGCC   CCGCUCG       GC CCUC    
target 5   C     GCG       UGGUAGU  A    A 3 PXN-AS1
Start: 165  End: 185
Energy: -31.7 kcal/mol
Align Score: 0.003901

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PXN-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-296-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CX3CR1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 12q24.23

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.