Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

9q34.11

lncRNA

LINC00963 ( ENSG00000204054)

miRNA

hsa-miR-324-3p (MIMAT0000762)

mRNA

CREBBP (ENSG00000005339)

Disease

BRCA

FDR

5.13E-34

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' ggUCGUCGUGGACCCCGUCa 5' hsa-miR-324-3p
            :| ||| | |||||||| 
target 5' ttGGAAGCCCATGGGGCAGg 3' LINC00963
Start: 256  End: 275
Energy: -24.25 kcal/mol
Align Score: 162
miRNA  3' ggUCGUCGUGGACCCCGUCa 5' hsa-miR-324-3p
            :| ||| | |||||||| 
target 5' ttGGAAGCCCATGGGGCAGc 3' LINC00963
Start: 737  End: 756
Energy: -24.33 kcal/mol
Align Score: 162
miRNA  3' ggUCGUCGUGGACCCCGUCa 5' hsa-miR-324-3p
            :| ||| | |||||||| 
target 5' ttGGAAGCCCATGGGGCAGa 3' LINC00963
Start: 370  End: 389
Energy: -24.34 kcal/mol
Align Score: 162
miRNA  3' ggUCGUCGUGGACCCCGUCa 5' hsa-miR-324-3p
            :| ||| | |||||||| 
target 5' ttGGAAGCCCATGGGGCAGa 3' LINC00963
Start: 182  End: 201
Energy: -24.34 kcal/mol
Align Score: 162
miRNA  3' ggUCGUCGUGGACCCCGUCa 5' hsa-miR-324-3p
            :| ||| | |||||||| 
target 5' ttGGAAGCCCATGGGGCAGc 3' LINC00963
Start: 175  End: 194
Energy: -24.33 kcal/mol
Align Score: 162
TargetScan target site prediction
miRNA  3'    GGUCGUCGUGGACCCCGUCA 5' hsa-miR-324-3p
                  |||    ||||||| 
target 5' CAGUUGGAAGCCCAUGGGGCAGA LINC00963
Start: 194  End: 201
Site type: 8mer-1a
Context++ Score: -0.46
miRNA  3'    GGUCGUCGUGGACCCCGUCA 5' hsa-miR-324-3p
                  |||    ||||||| 
target 5' CAGUUGGAAGCCCAUGGGGCAGA LINC00963
Start: 194  End: 201
Site type: 8mer-1a
Context++ Score: -0.46
RNAbybrid target site prediction
miRNA  3'                              A 5' hsa-miR-324-3p
           GGU  CGUCG     UGG  ACCCCGUC    
           CCA  GCAGU     GCC  UGGGGCAG    
target 5' A   UC     UGGAA   CA        G 3' LINC00963
Start: 246  End: 266
Energy: -33.6 kcal/mol
Align Score: 0.007196
miRNA  3'       U               CA 5' hsa-miR-324-3p
           GGUCG CG   UGGACCCCGU     
           CCGGC GC   ACCUGGGGCA     
target 5' G     C  CUG          A  3' LINC00963
Start: 322  End: 342
Energy: -36.1 kcal/mol
Align Score: 0.004294
miRNA  3'                              A 5' hsa-miR-324-3p
           GGU  CGUCG     UGG  ACCCCGUC    
           CCA  GCAGU     GCC  UGGGGCAG    
target 5' A   UC     UGGAA   CA        A 3' LINC00963
Start: 360  End: 380
Energy: -33.4 kcal/mol
Align Score: 0.004941
miRNA  3'      G    G            A 5' hsa-miR-324-3p
           GGUC UCGU GACCC   CGUC    
           CCAG AGCA CUGGG   GCAG    
target 5' U         G     ACU    A 3' LINC00963
Start: 724  End: 744
Energy: -31.6 kcal/mol
Align Score: 0.00888
miRNA  3'      G    G            A 5' hsa-miR-324-3p
           GGUC UCGU GACCC   CGUC    
           CCAG AGCA CUGGG   GCAG    
target 5' U         G     ACU    A 3' LINC00963
Start: 428  End: 448
Energy: -31.6 kcal/mol
Align Score: 0.007967

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC00963

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-324-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CREBBP

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 9q34.11

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.