Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q13

lncRNA

MIR4435-2HG ( ENSG00000172965)

miRNA

hsa-miR-345-5p (MIMAT0000772)

mRNA

NTRK3 (ENSG00000140538)

Disease

BRCA

FDR

1.46E-128

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 CU               CA         5 hsa-miR-345-5p
            CGGGACCU GAUCCU     GUCG    
            GCCCUGGG CUGGGA     CAGC    
target 5  U        C      AAAUG    A 3 MIR4435-2HG
Start: 308  End: 328
Energy: -36.4 kcal/mol
Align Score: 0.001694
miRNA  3             GAU    A      5 hsa-miR-345-5p
           CUCGG GACCU   CCUC GUCG    
           GGGCC CUGGG   GGAG CAGC    
target 5 A     A     GCC         C 3 MIR4435-2HG
Start: 430  End: 450
Energy: -32.1 kcal/mol
Align Score: 0.006873
miRNA  3             GAU    A      5 hsa-miR-345-5p
           CUCGG GACCU   CCUC GUCG    
           GGGCC CUGGG   GGAG CAGC    
target 5 A     A     GCC         C 3 MIR4435-2HG
Start: 212  End: 232
Energy: -32.1 kcal/mol
Align Score: 0.004487
miRNA  3         A    A             G 5 hsa-miR-345-5p
           CUCGG G CCUG     UCCUCAGUC    
           GAGCC C GGGC     AGGAGUCAG    
target 5 A     U A    CCAUC         A 3 MIR4435-2HG
Start: 941  End: 961
Energy: -33.9 kcal/mol
Align Score: 0.008292
miRNA  3 C    G        C           5 hsa-miR-345-5p
           UCGG ACCUGAUC   UCAGUCG    
           GGUC UGGGCUGG   GGUCGGU    
target 5 U    A        UCU       U 3 MIR4435-2HG
Start: 327  End: 347
Energy: -29.7 kcal/mol
Align Score: 0.007783

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for MIR4435-2HG

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-345-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for NTRK3

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q13

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.