Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10q24.32

lncRNA

RPARP-AS1 ( ENSG00000269609)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

GADD45A (ENSG00000116717)

Disease

BRCA

FDR

2.78E-9

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3        AA                 U      5 hsa-miR-370-3p
           UGGUCC        GGUGGG GUCG  CCG    
           GCUGGG        UCGCCC CGGC  GGC    
target 5 A      GAUCACCG      U    UU   A 3 RPARP-AS1
Start: 164  End: 184
Energy: -32.8 kcal/mol
Align Score: 0.004767
miRNA  3        AA                 U      5 hsa-miR-370-3p
           UGGUCC        GGUGGG GUCG  CCG    
           GCUGGG        UCGCCC CGGC  GGC    
target 5 A      GAUCACCG      U    UU   A 3 RPARP-AS1
Start: 150  End: 170
Energy: -32.8 kcal/mol
Align Score: 0.009678
miRNA  3 U                                      G 5 hsa-miR-370-3p
           GGUCCAA            GGUGGGGUCG      UCC    
           CCAGGUU            CCACCUCAGC      AGG    
target 5 U       CAAGCGAUUCUC          CUCCCG   A 3 RPARP-AS1
Start: 547  End: 567
Energy: -33.9 kcal/mol
Align Score: 0.008114
miRNA  3     U  A            UCG       5 hsa-miR-370-3p
           UGG CC     AGGUGGGG    UCCG    
           ACC GG     UCCACCCU    GGGC    
target 5 A   U  ACCUG        UGAA    U 3 RPARP-AS1
Start: 269  End: 289
Energy: -33.2 kcal/mol
Align Score: 0.002201
miRNA  3        AA     G       GU     5 hsa-miR-370-3p
           UGGUCC      G UGGGGUC  CCG    
           ACCAGG      C GCCUCGG  GGC    
target 5 C      GCGGCG G       GU   G 3 RPARP-AS1
Start: 240  End: 260
Energy: -38.4 kcal/mol
Align Score: 0.000277

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for RPARP-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for GADD45A

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10q24.32

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.