Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

17q21.31

lncRNA

MAP3K14-AS1 ( ENSG00000267278)

miRNA

hsa-miR-3940-5p (MIMAT0019229)

mRNA

USP28 (ENSG00000048028)

Disease

BRCA

FDR

2.60E-7

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3                        U         5 hsa-miR-3940-5p
           GUCUCGGG        CGGGGU   GGGUG    
           CGGGGCCC        GCUUCG   CCUGC    
target 5 C        GGGGCUGG      UGU     G 3 MAP3K14-AS1
Start: 24  End: 44
Energy: -29.3 kcal/mol
Align Score: 0.00909
miRNA  3         G                    G      5 hsa-miR-3940-5p
           GUCUCGG          CGGGGU    U GGUG    
           CAGGGCC          GCCCCA    A CCAC    
target 5 C       AGUGCUCAGG      CUGC G    G 3 MAP3K14-AS1
Start: 316  End: 336
Energy: -32.7 kcal/mol
Align Score: 0.003087
miRNA  3         G                    G      5 hsa-miR-3940-5p
           GUCUCGG          CGGGGU    U GGUG    
           CAGGGCC          GCCCCA    A CCAC    
target 5 C       AGUGCUCAGG      CUGC G    G 3 MAP3K14-AS1
Start: 382  End: 402
Energy: -32.7 kcal/mol
Align Score: 0.002661
miRNA  3         G     U        5 hsa-miR-3940-5p
           GUCUCGG CGGGG UGGGUG    
           CGGGGCU GCCUC ACUCAC    
target 5 G       G            U 3 MAP3K14-AS1
Start: 72  End: 92
Energy: -33.7 kcal/mol
Align Score: 0.00226
miRNA  3 GU UC      G           5 hsa-miR-3940-5p
            C  GGGCGG GUU GGGUG    
            G  CCCGCC CGA CCCAC    
target 5  C UC      G   C     A 3 MAP3K14-AS1
Start: 80  End: 100
Energy: -32.1 kcal/mol
Align Score: 0.007726

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for MAP3K14-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-3940-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for USP28

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 17q21.31

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.