Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10q22.2

lncRNA

ZNF503-AS2 ( ENSG00000237149)

miRNA

hsa-miR-874-3p (MIMAT0004911)

mRNA

AQP3 (ENSG00000165272)

Disease

BRCA

FDR

3.06E-10

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3         G                           5 hsa-miR-874-3p
           AGCCAGG AGCCC          GGUCC CGUC    
           UCGGUCU UUGGG          UCGGG GCGG    
target 5 C       G     GUCGCGGAGU     C    C 3 ZNF503-AS2
Start: 52  End: 72
Energy: -34.8 kcal/mol
Align Score: 0.001927
miRNA  3 A   A      C    UC       5 hsa-miR-874-3p
           GCC GGGAGC  CGG  CCGUC    
           CGG CUCUCG  GCC  GGCAG    
target 5 G   C      CU   U      U 3 ZNF503-AS2
Start: 506  End: 526
Energy: -32.5 kcal/mol
Align Score: 0.008067
miRNA  3 A   A   G           C  C 5 hsa-miR-874-3p
           GCC  GG AGC CCGGUCC GU    
           CGG  CC UUG GGCCAGG CA    
target 5 G   CG  G   A       A  C 3 ZNF503-AS2
Start: 882  End: 902
Energy: -32.8 kcal/mol
Align Score: 0.008249
miRNA  3 A   A      C    UC       5 hsa-miR-874-3p
           GCC GGGAGC  CGG  CCGUC    
           CGG CUCUCG  GCC  GGCAG    
target 5 G   C      CU   U      U 3 ZNF503-AS2
Start: 324  End: 344
Energy: -32.5 kcal/mol
Align Score: 0.003929

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZNF503-AS2

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-874-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for AQP3

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10q22.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.