Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q13

lncRNA

MIR4435-2HG ( ENSG00000172965)

miRNA

hsa-miR-874-3p (MIMAT0004911)

mRNA

AQP3 (ENSG00000165272)

Disease

BRCA

FDR

8.29E-130

Reported as biomarkers
0

Circulating

0

Drug resistent

0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
NA

                         
NA

TargetScan target site prediction
                                           
NA

                         
NA

RNAbybrid target site prediction
miRNA  3 AG      AG                        UC 5 hsa-miR-874-3p
CCAGGG CCCGG UCCCG
GGUCCC GGGCU GGGGU
target 5 A AGGAA GUGAUCUGCCU C 3 MIR4435-2HG
Start: 604  End: 624
Energy: -33 kcal/mol
Align Score: 0.005333
miRNA  3 A   AG  A   C   G         5 hsa-miR-874-3p
GCC GG G CCG UCCCGUC
UGG CC C GGU AGGGCAG
target 5 A AG ACA C G G 3 MIR4435-2HG
Start: 413  End: 433
Energy: -30.8 kcal/mol
Align Score: 0.00922
miRNA  3 AGCC     G     U  CGUC 5 hsa-miR-874-3p
AGGGA CCCGG CC
UCCCU GGGCC GG
target 5 U G U U 3 MIR4435-2HG
Start: 337  End: 357
Energy: -30.6 kcal/mol
Align Score: 0.007247
miRNA  3 AG  A     G       C      5 hsa-miR-874-3p
CC GG GA CCCGGUC CGUC
GG CC CU GGGCCGG GCAG
target 5 A G A G A C 3 MIR4435-2HG
Start: 430  End: 450
Energy: -35.1 kcal/mol
Align Score: 0.002295
miRNA  3 AG  A     G       C      5 hsa-miR-874-3p
CC GG GA CCCGGUC CGUC
GG CC CU GGGCCGG GCAG
target 5 A G A G A C 3 MIR4435-2HG
Start: 212  End: 232
Energy: -35.1 kcal/mol
Align Score: 0.001438

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for MIR4435-2HG

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-874-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for AQP3

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q13

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.