Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

14q23.1

lncRNA

PSMA3-AS1 ( ENSG00000257621)

miRNA

hsa-miR-93-5p (MIMAT0000093)

mRNA

PDCD4 (ENSG00000150593)

Disease

BRCA

FDR

9.53E-41

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' gaUGGACGUGCUUGUCGUGAAAc 5' hsa-miR-93-5p
            :||||:|    ||||||||| 
target 5' gtGCCTGTAATCCCAGCACTTTg 3' PSMA3-AS1
Start: 557  End: 579
Energy: -29.07 kcal/mol
Align Score: 165
miRNA  3' gaUGGACGUGCUUGUCGUGAAAc 5' hsa-miR-93-5p
            :||||:|    ||||||||| 
target 5' gtGCCTGTAATCCCAGCACTTTg 3' PSMA3-AS1
Start: 364  End: 386
Energy: -29.07 kcal/mol
Align Score: 165
miRNA  3' gaUGGACGUGCUUGUCGUGAAAc 5' hsa-miR-93-5p
            :||||:|    ||||||||| 
target 5' gtGCCTGTAATCCCAGCACTTTg 3' PSMA3-AS1
Start: 509  End: 531
Energy: -29.07 kcal/mol
Align Score: 165
miRNA  3' gaUGGACGUGCUUGUCGUGAAAc 5' hsa-miR-93-5p
            :||||:|    ||||||||| 
target 5' gtGCCTGTAATCCCAGCACTTTg 3' PSMA3-AS1
Start: 281  End: 303
Energy: -29.07 kcal/mol
Align Score: 165
miRNA  3' gaUGGACGUGCUUGUCGUGAAAc 5' hsa-miR-93-5p
            :||||:|    ||||||||| 
target 5' gtGCCTGTAATCCCAGCACTTTg 3' PSMA3-AS1
Start: 562  End: 584
Energy: -29.07 kcal/mol
Align Score: 165
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3' G        GCUU            5' hsa-miR-93-5p
           AUGGACGU    GUCGUGAAAC    
           UGCCUGUA    CAGCACUUUG    
target 5' G        AUCC          G 3' PSMA3-AS1
Start: 364  End: 384
Energy: -32.8 kcal/mol
Align Score: 0.007924
miRNA  3' G        GCUU            5' hsa-miR-93-5p
           AUGGACGU    GUCGUGAAAC    
           UGCCUGUA    CAGCACUUUG    
target 5' G        AUCC          G 3' PSMA3-AS1
Start: 509  End: 529
Energy: -32.8 kcal/mol
Align Score: 0.00673
miRNA  3' G        GCUU            5' hsa-miR-93-5p
           AUGGACGU    GUCGUGAAAC    
           UGCCUGUA    CAGCACUUUG    
target 5' G        AUCC          G 3' PSMA3-AS1
Start: 281  End: 301
Energy: -32.8 kcal/mol
Align Score: 0.003883
miRNA  3' G        GCUU            5' hsa-miR-93-5p
           AUGGACGU    GUCGUGAAAC    
           UGCCUGUA    CAGCACUUUG    
target 5' G        AUCC          G 3' PSMA3-AS1
Start: 562  End: 582
Energy: -32.8 kcal/mol
Align Score: 0.005302
miRNA  3' GA       GCUU            5' hsa-miR-93-5p
            UGGACGU    GUCGUGAAAC    
            GCCUGUA    CAGCACUUUG    
target 5'  C       AUCC          G 3' PSMA3-AS1
Start: 319  End: 339
Energy: -31.8 kcal/mol
Align Score: 0.008843

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PSMA3-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-93-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for PDCD4

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 14q23.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.