Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

11q14.1

lncRNA

RAB30-AS1 ( ENSG00000246067)

miRNA

hsa-miR-940 (MIMAT0004983)

mRNA

CD274 (ENSG00000120217)

Disease

BRCA

FDR

8.02E-29

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 CC     C          A   AA 5 hsa-miR-940
            CCUCG   CCCC GGG CGG     
            GGAGC   GGGG CUC GCC     
target 5  A     AAA    A   G   G  3 RAB30-AS1
Start: 8  End: 28
Energy: -31.7 kcal/mol
Align Score: 0.005552
miRNA  3 CC     C          A   AA 5 hsa-miR-940
            CCUCG   CCCC GGG CGG     
            GGAGC   GGGG CUC GCC     
target 5  A     AAA    A   G   G  3 RAB30-AS1
Start: 8  End: 28
Energy: -31.7 kcal/mol
Align Score: 0.004369
miRNA  3                C      A        AA 5 hsa-miR-940
           CCC  CUC GCCCC    GGG      CGG     
           GGG  GAG CGGGG    CCC      GCC     
target 5 C   CA   A     UUUU   AUGUUA   A  3 RAB30-AS1
Start: 26  End: 46
Energy: -29.3 kcal/mol
Align Score: 0.006668
miRNA  3                       CC    A        5 hsa-miR-940
           CCCCU            CGCC  CGGG  CGGAA    
           GGGGA            GCGG  GCUC  GCCUU    
target 5 A     UAUUGGCCAGGU    UC    AC     U 3 RAB30-AS1
Start: 192  End: 212
Energy: -31.1 kcal/mol
Align Score: 0.006818

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for RAB30-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-940

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CD274

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 11q14.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.