Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

11q12.3

lncRNA

SNHG1 ( ENSG00000255717)

miRNA

hsa-miR-760 (MIMAT0004957)

mRNA

HIST1H2AD (ENSG00000196866)

Disease

ESCA

FDR

6.72E-10

Reported as biomarkers
1

Circulating
0

Drug resistent
14

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' aggGGUGUCUGGGUCUCGGc 5' hsa-miR-760
             :| :|| ||||||||| 
target 5' ctgTCCTAGTCCCAGAGCCt 3' SNHG1
Start: 1884  End: 1903
Energy: -25.66 kcal/mol
Align Score: 161
miRNA  3' aggGGUGUCUGGGUCUCGGc 5' hsa-miR-760
             ::|||| ||||||||| 
target 5' aagTTACAGTCCCAGAGCCt 3' SNHG1
Start: 357  End: 376
Energy: -27.35 kcal/mol
Align Score: 169
miRNA  3' aggGGUGUCUGGGUCUCGGc 5' hsa-miR-760
             :| :|| ||||||||| 
target 5' ctgTCCTAGTCCCAGAGCCt 3' SNHG1
Start: 466  End: 485
Energy: -25.66 kcal/mol
Align Score: 161
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3' A                   U         C 5' hsa-miR-760
           GGGG           UGUC GGGUCUCGG    
           CUCC           ACAG CCCAGAGCC    
target 5' A    AGGCUGAAGUU    U         U 3' SNHG1
Start: 346  End: 366
Energy: -33.7 kcal/mol
Align Score: 0.002462
miRNA  3'              U         C 5' hsa-miR-760
           AGGGGU   GUC GGGUCUCGG    
           UCUCUG   UAG CCCAGAGCC    
target 5' C      UCC   U         U 3' SNHG1
Start: 462  End: 482
Energy: -31.6 kcal/mol
Align Score: 0.00575
miRNA  3' AG     U              C 5' hsa-miR-760
            GGGUG  CUGGGU  CUCGG    
            CCUGC  GGCUCA  GGGCC    
target 5'  A     UU      AA     A 3' SNHG1
Start: 206  End: 226
Energy: -27.4 kcal/mol
Align Score: 0.008538
miRNA  3' AG     U               C 5' hsa-miR-760
            GGGUG C    UGGGUCUCGG    
            CCCAC G    GCCCAGGGUC    
target 5'  G     U AUCU          A 3' SNHG1
Start: 731  End: 751
Energy: -32 kcal/mol
Align Score: 0.008538
miRNA  3 A                   U         C 5 hsa-miR-760
           GGGG           UGUC GGGUCUCGG    
           CUCC           ACAG CCCAGAGCC    
target 5 A    AGGCUGAAGUU    U         U 3 SNHG1
Start: 346  End: 366
Energy: -33.7 kcal/mol
Align Score: 0.002462

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SNHG1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-760

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for HIST1H2AD

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 11q12.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.