Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p13.3

lncRNA

PCBP1-AS1 ( ENSG00000179818)

miRNA

hsa-miR-1291 (MIMAT0005881)

mRNA

ERN1 (ENSG00000178607)

Disease

COAD

FDR

1.70E-7

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'   UGACGACCAGAAGUCAGUCCCGGU 5' hsa-miR-1291
                            ||||||| 
target 5'    ACGCUGCUCAUCUAGCAGGGCCA PCBP1-AS1
Start: 303  End: 310
Site type: 8mer-1a
Context++ Score: -0.421
miRNA  3' UGACGACCAGAAGUCAGUCCCGGU 5' hsa-miR-1291
                          ||||||| 
target 5'  ACCAGUUACUAUUUGCAGGGCCA PCBP1-AS1
Start: 472  End: 479
Site type: 8mer-1a
Context++ Score: -0.429
miRNA  3' UGACGACCAGAAGUCAGUCCCGGU 5' hsa-miR-1291
                          ||||||| 
target 5'  ACCAGUUACUAUUUGCAGGGCCA PCBP1-AS1
Start: 345  End: 352
Site type: 8mer-1a
Context++ Score: -0.43
RNAbybrid target site prediction
miRNA  3     C               G           5 hsa-miR-1291
           UGA  GACCAGAA GU CA U  CCCGGU    
           GCU  CUGGUCUU CG GU G  GGGCCA    
target 5 G   UC        G  U  G CU      U 3 PCBP1-AS1
Start: 490  End: 510
Energy: -31.2 kcal/mol
Align Score: 0.007926
miRNA  3     C               G           5 hsa-miR-1291
           UGA  GACCAGAA GU CA U  CCCGGU    
           GCU  CUGGUCUU CG GU G  GGGCCA    
target 5 G   UC        G  U  G CU      U 3 PCBP1-AS1
Start: 554  End: 574
Energy: -31.2 kcal/mol
Align Score: 0.00893
miRNA  3 UGA        AG            U 5 hsa-miR-1291
             CGACCAGA   UCAGUC CCGG    
             GCUGGUCU   GGUCGG GGCC    
target 5   G        GAA      A    U 3 PCBP1-AS1
Start: 1  End: 21
Energy: -38.9 kcal/mol
Align Score: 0.000953
miRNA  3    A         AG            U 5 hsa-miR-1291
           UG  CGACCAGA   UCAGUC CCGG    
           AC  GCUGGUCU   GGUCGG GGCC    
target 5 C  AG        GAA      A    U 3 PCBP1-AS1
Start: 132  End: 152
Energy: -38.9 kcal/mol
Align Score: 0.000628
miRNA  3    A         AG            U 5 hsa-miR-1291
           UG  CGACCAGA   UCAGUC CCGG    
           AC  GCUGGUCU   GGUCGG GGCC    
target 5 C  AG        GAA      A    U 3 PCBP1-AS1
Start: 134  End: 154
Energy: -38.9 kcal/mol
Align Score: 0.000728

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PCBP1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1291

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ERN1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p13.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.