Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q13

lncRNA

MIR4435-2HG ( ENSG00000172965)

miRNA

hsa-miR-1266-5p (MIMAT0005920)

mRNA

TERT (ENSG00000164362)

Disease

PAAD

FDR

6.70E-5

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3       A    A   U                      5 hsa-miR-1266-5p
           UCGGG CAAG  UG CGGG           ACUCC    
           GGCCU GUUC  AC GCCC           UGAGG    
target 5 G     G    CA  U    ACUGUGGACUC     C 3 MIR4435-2HG
Start: 344  End: 364
Energy: -30.5 kcal/mol
Align Score: 0.007955
miRNA  3          AA  A         GA   C 5 hsa-miR-1266-5p
           UCGG GAC   G    UGUCGG  CUC    
           GGCC CUG   C    GCAGCC  GAG    
target 5 G    A   GGG CGGA      GA   A 3 MIR4435-2HG
Start: 213  End: 233
Energy: -30.6 kcal/mol
Align Score: 0.00836
miRNA  3       A    A   U                      5 hsa-miR-1266-5p
           UCGGG CAAG  UG CGGG           ACUCC    
           GGCCU GUUC  AC GCCC           UGAGG    
target 5 G     G    CA  U    ACUGUGGACUC     C 3 MIR4435-2HG
Start: 256  End: 276
Energy: -30.5 kcal/mol
Align Score: 0.006033
miRNA  3       A    A   U                      5 hsa-miR-1266-5p
           UCGGG CAAG  UG CGGG           ACUCC    
           GGCCU GUUC  AC GCCC           UGAGG    
target 5 G     G    CA  U    ACUGUGGACUC     C 3 MIR4435-2HG
Start: 390  End: 410
Energy: -30.5 kcal/mol
Align Score: 0.008566

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for MIR4435-2HG

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1266-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for TERT

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q13

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.