Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

20q11.23

lncRNA

SNHG17 ( ENSG00000196756)

miRNA

hsa-miR-1266-5p (MIMAT0005920)

mRNA

TERT (ENSG00000164362)

Disease

HNSC

FDR

5.51E-7

Reported as biomarkers
0

Circulating
0

Drug resistent
1

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' ucGGGACAAGAUGU-CGGGACUCc 5' hsa-miR-1266-5p
            |:||| |||:||  ||||||| 
target 5' caCTCTGATCTGCACCCCCTGAGg 3' SNHG17
Start: 202  End: 225
Energy: -33.89 kcal/mol
Align Score: 172
miRNA  3' ucGGGACAAGAUGU-CGGGACUCc 5' hsa-miR-1266-5p
            |:||| |||:||  ||||||| 
target 5' caCTCTGATCTGCACCCCCTGAGg 3' SNHG17
Start: 142  End: 165
Energy: -33.89 kcal/mol
Align Score: 172
miRNA  3' ucGGGACAAGAUGU-CGGGACUCc 5' hsa-miR-1266-5p
            |:||| |||:||  ||||||| 
target 5' caCTCTGATCTGCACCCCCTGAGg 3' SNHG17
Start: 146  End: 169
Energy: -33.89 kcal/mol
Align Score: 172
miRNA  3' ucGGGACAAGAUGU-CGGGACUCc 5' hsa-miR-1266-5p
            |:||| |||:||  ||||||| 
target 5' caCTCTGATCTGCACCCCCTGAGg 3' SNHG17
Start: 372  End: 395
Energy: -33.89 kcal/mol
Align Score: 172
miRNA  3' ucGGGACAAGAUGU-CGGGACUCc 5' hsa-miR-1266-5p
            |:||| |||:||  ||||||| 
target 5' caCTCTGATCTGCACCCCCTGAGg 3' SNHG17
Start: 373  End: 396
Energy: -33.89 kcal/mol
Align Score: 172
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3'           A      C           5' hsa-miR-1266-5p
           UCG G GAC AGAUGU  GGGACUCC    
           AGC C CUG UCUGCA  CCCUGAGG    
target 5' C   A U   A      CC        G 3' SNHG17
Start: 199  End: 219
Energy: -34.6 kcal/mol
Align Score: 0.003873
miRNA  3'           A      C           5' hsa-miR-1266-5p
           UCG G GAC AGAUGU  GGGACUCC    
           AGC C CUG UCUGCA  CCCUGAGG    
target 5' C   A U   A      CC        G 3' SNHG17
Start: 143  End: 163
Energy: -34.6 kcal/mol
Align Score: 0.003418
miRNA  3'       A  AAGA       GA       5' hsa-miR-1266-5p
           UCGGG  C     UGUCGG   CUCC    
           GGCCC  G     GCGGCC   GAGG    
target 5' A     CG GGAAG      AGA    U 3' SNHG17
Start: 213  End: 233
Energy: -30.7 kcal/mol
Align Score: 0.009763
miRNA  3'           A      C           5' hsa-miR-1266-5p
           UCG G GAC AGAUGU  GGGACUCC    
           AGC C CUG UCUGCA  CCCUGAGG    
target 5' C   A U   A      CC        G 3' SNHG17
Start: 369  End: 389
Energy: -34.6 kcal/mol
Align Score: 0.001822
miRNA  3'           A      C           5' hsa-miR-1266-5p
           UCG G GAC AGAUGU  GGGACUCC    
           AGC C CUG UCUGCA  CCCUGAGG    
target 5' C   A U   A      CC        G 3' SNHG17
Start: 370  End: 390
Energy: -34.6 kcal/mol
Align Score: 0.002856

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SNHG17

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1266-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for TERT

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 20q11.23

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.