Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

1p22.1

lncRNA

CCDC18-AS1 ( ENSG00000223745)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

GADD45A (ENSG00000116717)

Disease

HNSC

FDR

9.37E-14

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3       C                   U       5 hsa-miR-370-3p
           UGGUC    AAGGUGGG    GUCG   CCG    
           GCCAG    UUCCGCCU    CGGU   GGC    
target 5 U     CAGC        GCUA    CCU   A 3 CCDC18-AS1
Start: 35  End: 55
Energy: -31.2 kcal/mol
Align Score: 0.009444
miRNA  3                                   U     5 hsa-miR-370-3p
           UG GUC  CAAGGUG            GGGUCG CCG    
           GC CGG  GUUCCAC            UCUGGC GGC    
target 5 U  A   UU       AUGACAGAACUA      U   A 3 CCDC18-AS1
Start: 25  End: 45
Energy: -28.4 kcal/mol
Align Score: 0.009431
miRNA  3 U                    UG       UCCG 5 hsa-miR-370-3p
           GGUCCA           AGG  GG GUCG       
           CCAGGU           UCC  CC CAGC       
target 5 C      UCAAGCGAUUC   UG  U    C    3 CCDC18-AS1
Start: 4  End: 24
Energy: -30 kcal/mol
Align Score: 0.008566
miRNA  3 U      A                                  G 5 hsa-miR-370-3p
           GGUCCA       GGUGGGG               UCGUCC    
           CCGGGU       CCGCCCU               GGCGGG    
target 5 U      GUGGCUG       UCCCCCACCCACGCC      A 3 CCDC18-AS1
Start: 171  End: 191
Energy: -34.6 kcal/mol
Align Score: 0.004853
miRNA  3 U      A                                   5 hsa-miR-370-3p
           GGUCCA       GGUGGGGUCG             UCCG    
           UCAGGU       CUACCUCAGC             GGGU    
target 5 C      GAUUCAC          UUCCCGACGUACU    U 3 CCDC18-AS1
Start: 168  End: 188
Energy: -30.8 kcal/mol
Align Score: 0.005612

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for CCDC18-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for GADD45A

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 1p22.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.