Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

8q23.1

lncRNA

ZFPM2-AS1 ( ENSG00000251003)

miRNA

hsa-let-7b-5p (MIMAT0000063)

mRNA

TNFRSF10B (ENSG00000120889)

Disease

KIRC

FDR

3.39E-2

Reported as biomarkers
0

Circulating
0

Drug resistent
1

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' uuGGUG-UGUUGGAUGAUGGAGu 5' hsa-let-7b-5p
            :||| :|||||| ||||||| 
target 5' acTCACTGCAACCT-CTACCTCc 3' ZFPM2-AS1
Start: 257  End: 278
Energy: -27.13 kcal/mol
Align Score: 169
miRNA  3' uuGGUG-UGUUGGAUGAUGGAGu 5' hsa-let-7b-5p
            :||| :|||||| ||||||| 
target 5' acTCACTGCAACCT-CTACCTCc 3' ZFPM2-AS1
Start: 199  End: 220
Energy: -27.13 kcal/mol
Align Score: 169
miRNA  3' uuGGUG-UGUUGGAUGAUGGAGu 5' hsa-let-7b-5p
            :||| :|||||| ||||||| 
target 5' acTCACTGCAACCT-CTACCTCc 3' ZFPM2-AS1
Start: 200  End: 221
Energy: -27.13 kcal/mol
Align Score: 169
miRNA  3' uuGGUG-UGUUGGAUGAUGGAGu 5' hsa-let-7b-5p
            :||| :|||||| ||||||| 
target 5' acTCACTGCAACCT-CTACCTCc 3' ZFPM2-AS1
Start: 111  End: 132
Energy: -27.13 kcal/mol
Align Score: 169
miRNA  3' uuGGUG-UGUUGGAUGAUGGAGu 5' hsa-let-7b-5p
            :||| :|||||| ||||||| 
target 5' acTCACTGCAACCT-CTACCTCc 3' ZFPM2-AS1
Start: 185  End: 206
Energy: -27.13 kcal/mol
Align Score: 169
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3'                 U       U 5' hsa-let-7b-5p
           UUG GUG UGUUGGA GAUGGAG    
           AAC CAC GCAACCU CUACCUC    
target 5' C   U   U               C 3' ZFPM2-AS1
Start: 198  End: 218
Energy: -30.7 kcal/mol
Align Score: 0.009022
miRNA  3'                 U       U 5' hsa-let-7b-5p
           UUG GUG UGUUGGA GAUGGAG    
           AAC CAC GCAACCU CUACCUC    
target 5' C   U   U               C 3' ZFPM2-AS1
Start: 109  End: 129
Energy: -30.7 kcal/mol
Align Score: 0.009278
miRNA  3'                 U       U 5' hsa-let-7b-5p
           UUG GUG UGUUGGA GAUGGAG    
           AAC CAC GCAACCU CUACCUC    
target 5' C   U   U               C 3' ZFPM2-AS1
Start: 183  End: 203
Energy: -30.7 kcal/mol
Align Score: 0.007453
miRNA  3'                 U       U 5' hsa-let-7b-5p
           UUG GUG UGUUGGA GAUGGAG    
           AAC CAC GCAACCU CUACCUC    
target 5' C   U   U               C 3' ZFPM2-AS1
Start: 192  End: 212
Energy: -30.7 kcal/mol
Align Score: 0.006738
miRNA  3'                 U       U 5' hsa-let-7b-5p
           UUG GUG UGUUGGA GAUGGAG    
           AAC CAC GCAACCU CUACCUC    
target 5' C   U   U               C 3' ZFPM2-AS1
Start: 322  End: 342
Energy: -30.7 kcal/mol
Align Score: 0.004948

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for ZFPM2-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-let-7b-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for TNFRSF10B

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 8q23.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.