Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q21.3

lncRNA

DARS-AS1 ( ENSG00000231890)

miRNA

hsa-miR-296-3p (MIMAT0004679)

mRNA

ICAM1 (ENSG00000090339)

Disease

KIRC

FDR

4.19E-7

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 CC      A      UU       5 hsa-miR-296-3p
            UCUCGG GGUGGG  GGGAG    
            AGGGCC CCACUC  CCCUC    
target 5  U             C      C 3 DARS-AS1
Start: 142  End: 162
Energy: -33 kcal/mol
Align Score: 0.004907
miRNA  3 CC      A      UU       5 hsa-miR-296-3p
            UCUCGG GGUGGG  GGGAG    
            AGGGCC CCACUC  CCCUC    
target 5  U             C      C 3 DARS-AS1
Start: 99  End: 119
Energy: -33 kcal/mol
Align Score: 0.004876
miRNA  3      U                       G 5 hsa-miR-296-3p
           CCUC CGGAGG     UGGGU  UGGGA    
           GGAG GCCUCU     AUCCA  GCCCU    
target 5 A           UCGCA     UU     G 3 DARS-AS1
Start: 318  End: 338
Energy: -33.9 kcal/mol
Align Score: 0.001661
miRNA  3            GA            UU       5 hsa-miR-296-3p
           CCU   CUCG        GGUGGG  GGGAG    
           GGA   GGGC        CCACCC  CCCUC    
target 5 C   ACU    AGUGGACA      U      G 3 DARS-AS1
Start: 3  End: 23
Energy: -32.4 kcal/mol
Align Score: 0.003402
miRNA  3 CC      A   G     G     5 hsa-miR-296-3p
            UCUCGG GGU GGUUG GAG    
            GGAGCC CUA CCAAC CUC    
target 5  U          G     A   U 3 DARS-AS1
Start: 200  End: 220
Energy: -31 kcal/mol
Align Score: 0.008469

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for DARS-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-296-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ICAM1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q21.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.