Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

3p25.3

lncRNA

THUMPD3-AS1 ( ENSG00000206573)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

LIN28A (ENSG00000131914)

Disease

KIRC

FDR

1.87E-5

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3' UGGUCCAAGGUGGG----GUCGUCCG 5' hsa-miR-370-3p
                |||||       ||||||| 
target 5'    GGAUUCCAAAACACACAGCAGGA THUMPD3-AS1
Start: 3067  End: 3074
Site type: 8mer-1a
Context++ Score: -0.43
RNAbybrid target site prediction
miRNA  3          G U             G 5 hsa-miR-370-3p
           UGGUCCAA G GGGG   UCGUCC    
           GCCAGGUU C CCUU   GGCAGG    
target 5 A        G U    GAG      A 3 THUMPD3-AS1
Start: 400  End: 420
Energy: -34.3 kcal/mol
Align Score: 0.003157
miRNA  3 U                UCG       5 hsa-miR-370-3p
           GGUCCAA GGUGG GG    UCCG    
           CCGGGUU CCACC CC    GGGC    
target 5 C       C     G  UGAA    G 3 THUMPD3-AS1
Start: 17  End: 37
Energy: -35.5 kcal/mol
Align Score: 0.000811
miRNA  3 UG               UCG       5 hsa-miR-370-3p
            GUCCAA GGUGG GG    UCCG    
            CGGGUU CCACC CC    GGGC    
target 5         C     G  UGAA    G 3 THUMPD3-AS1
Start: 1  End: 21
Energy: -32.6 kcal/mol
Align Score: 0.006392
miRNA  3 UG               UCG       5 hsa-miR-370-3p
            GUCCAA GGUGG GG    UCCG    
            CGGGUU CCACC CC    GGGC    
target 5         C     G  UGAA    G 3 THUMPD3-AS1
Start: 1  End: 21
Energy: -32.6 kcal/mol
Align Score: 0.003695
miRNA  3          G U             G 5 hsa-miR-370-3p
           UGGUCCAA G GGGG   UCGUCC    
           GCCAGGUU C CCUU   GGCAGG    
target 5 A        G U    GAG      A 3 THUMPD3-AS1
Start: 391  End: 411
Energy: -34.3 kcal/mol
Align Score: 0.004112

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for THUMPD3-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for LIN28A

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 3p25.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.