Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q21.3

lncRNA

DARS-AS1 ( ENSG00000231890)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

LIN28A (ENSG00000131914)

Disease

KIRC

FDR

6.99E-7

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'    UGGUCCAAGGUGGGGUCGUCCG 5' hsa-miR-370-3p
                           ||||||| 
target 5'   UCUUUUCUCUGAAGACAGCAGGA DARS-AS1
Start: 503  End: 510
Site type: 8mer-1a
Context++ Score: -0.434
RNAbybrid target site prediction
miRNA  3        AA              U            5 hsa-miR-370-3p
           UGGUCC         GGUGGGG     CGUCCG    
           ACUGGG         CCACCCU     GCAGGC    
target 5 A      CAGUGGACA       CCCUC      U 3 DARS-AS1
Start: 304  End: 324
Energy: -32.9 kcal/mol
Align Score: 0.00509
miRNA  3        AA              U            5 hsa-miR-370-3p
           UGGUCC         GGUGGGG     CGUCCG    
           ACUGGG         CCACCCU     GCAGGC    
target 5 A      CAGUGGACA       CCCUC      U 3 DARS-AS1
Start: 261  End: 281
Energy: -32.9 kcal/mol
Align Score: 0.005058
miRNA  3        AA              U            5 hsa-miR-370-3p
           UGGUCC         GGUGGGG     CGUCCG    
           ACUGGG         CCACCCU     GCAGGC    
target 5 A      CAGUGGACA       CCCUC      U 3 DARS-AS1
Start: 146  End: 166
Energy: -32.9 kcal/mol
Align Score: 0.00245
miRNA  3        AA              U            5 hsa-miR-370-3p
           UGGUCC         GGUGGGG     CGUCCG    
           ACUGGG         CCACCCU     GCAGGC    
target 5 A      CAGUGGACA       CCCUC      U 3 DARS-AS1
Start: 6  End: 26
Energy: -32.9 kcal/mol
Align Score: 0.002807
miRNA  3                                          5 hsa-miR-370-3p
           UGGUC         CAAGGU     GGGGUCG  UCCG    
           GCCAG         GUUCCA     CCCCAGU  AGGC    
target 5 G     CCCCCCGUU      GCCAU       UC    A 3 DARS-AS1
Start: 213  End: 233
Energy: -36.8 kcal/mol
Align Score: 0.000443

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for DARS-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for LIN28A

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q21.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.