Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2p13.3

lncRNA

PCBP1-AS1 ( ENSG00000179818)

miRNA

hsa-miR-654-5p (MIMAT0003330)

mRNA

EPSTI1 (ENSG00000133106)

Disease

KIRP

FDR

6.86E-5

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'  CGUGUACAAGACGCCGGGUGGU 5' hsa-miR-654-5p
                         ||||||| 
target 5' GCUGGGAUUGCAGGUGCCCACCA PCBP1-AS1
Start: 244  End: 251
Site type: 8mer-1a
Context++ Score: -0.429
miRNA  3'  CGUGUACAAGACGCCGGGUGGU 5' hsa-miR-654-5p
                         ||||||| 
target 5' GCUGGGAUUGCAGGUGCCCACCA PCBP1-AS1
Start: 400  End: 407
Site type: 8mer-1a
Context++ Score: -0.476
miRNA  3'  CGUGUACAAGACGCCGGGUGGU 5' hsa-miR-654-5p
                         ||||||| 
target 5' GCUGGGAUUGCAGGUGCCCACCA PCBP1-AS1
Start: 335  End: 342
Site type: 8mer-1a
Context++ Score: -0.477
RNAbybrid target site prediction
miRNA  3       A           C            5 hsa-miR-654-5p
           CGUGU   CA    AGA GCCGGGUGGU    
           GUGCA   GU    UCU CGGCUCACCA    
target 5 A     GUG  GCAA              C 3 PCBP1-AS1
Start: 334  End: 354
Energy: -30.8 kcal/mol
Align Score: 0.009335
miRNA  3       A           C            5 hsa-miR-654-5p
           CGUGU   CA    AGA GCCGGGUGGU    
           GUGCA   GU    UCU CGGCUCACCA    
target 5 A     GUG  GCAA              C 3 PCBP1-AS1
Start: 57  End: 77
Energy: -30.8 kcal/mol
Align Score: 0.007555
miRNA  3 C      AAG   G           5 hsa-miR-654-5p
           GUGUAC    AC CCGGGUGGU    
           CACAUG    UG GGCCCAUCA    
target 5 U      GCCA  A         U 3 PCBP1-AS1
Start: 253  End: 273
Energy: -31.8 kcal/mol
Align Score: 0.006363
miRNA  3 CG     A   C            5 hsa-miR-654-5p
            UGUAC AGA GCCGGGUGGU    
            GCAUG UCU CGGCUCAUCA    
target 5  G     A              C 3 PCBP1-AS1
Start: 419  End: 439
Energy: -31.2 kcal/mol
Align Score: 0.007143
miRNA  3 CG     A   C            5 hsa-miR-654-5p
            UGUAC AGA GCCGGGUGGU    
            GCAUG UCU CGGCUCAUCA    
target 5  G     A              C 3 PCBP1-AS1
Start: 254  End: 274
Energy: -31.2 kcal/mol
Align Score: 0.003497

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PCBP1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-654-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for EPSTI1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2p13.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.