Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

19q11

lncRNA

CTC-459F4.3 ( ENSG00000267575)

miRNA

hsa-miR-1254 (MIMAT0005905)

mRNA

CCAR1 (ENSG00000060339)

Disease

LGG

FDR

6.22E-4

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'  UGACGUCCGAGGUCGAAGGUCCGA 5' hsa-miR-1254
                           ||||||| 
target 5'   GAGAAAACCCUAAUUUCCAGGCA CTC-459F4.3
Start: 410  End: 417
Site type: 8mer-1a
Context++ Score: -0.454
miRNA  3'  UGACGUCCGAGGUCGAAGGUCCGA 5' hsa-miR-1254
                           ||||||| 
target 5'   GAGAAAACCCUAAUUUCCAGGCA CTC-459F4.3
Start: 446  End: 453
Site type: 8mer-1a
Context++ Score: -0.454
RNAbybrid target site prediction
miRNA  3 UG        AGGU         GA 5 hsa-miR-1254
            AC GUCCG    CGAAGGUCC     
            UG CAGGC    GCUUCCAGG     
target 5  G  C     AU           G  3 CTC-459F4.3
Start: 331  End: 351
Energy: -32.8 kcal/mol
Align Score: 0.004796
miRNA  3      G     G    AA             5 hsa-miR-1254
           UGAC UCCGA GUCG      GGUCCGA    
           GCUG AGGCU CGGC      CCAGGCU    
target 5 A          G    CCAGGC       G 3 CTC-459F4.3
Start: 618  End: 638
Energy: -37.2 kcal/mol
Align Score: 0.002426
miRNA  3 UGA G   GA      A          A 5 hsa-miR-1254
             C UCC  GGUCGA    GGU CCG    
             G AGG  CCGGCU    CCA GGC    
target 5   C G   GA      GAAG   U   A 3 CTC-459F4.3
Start: 702  End: 722
Energy: -33.5 kcal/mol
Align Score: 0.004504
miRNA  3       UC      U           C A 5 hsa-miR-1254
           UGACG  CGAG G CGA   AGGUC G    
           GCUGC  GCUC C GCU   UCCAG C    
target 5 U     U     U U   UUC     C A 3 CTC-459F4.3
Start: 251  End: 271
Energy: -29.9 kcal/mol
Align Score: 0.008503
miRNA  3 UGA  U         A       G      A 5 hsa-miR-1254
             CG CCGAGGUCG      AG   UCCG    
             GC GGUUCCAGC      UC   GGGC    
target 5   G            CGUUAG  ACA    G 3 CTC-459F4.3
Start: 9  End: 29
Energy: -32.4 kcal/mol
Align Score: 0.003809

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for CTC-459F4.3

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1254

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for CCAR1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 19q11

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.