Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

8q24.3

lncRNA

C8orf31 ( ENSG00000177335)

miRNA

hsa-miR-185-3p (MIMAT0004611)

mRNA

AKT1 (ENSG00000142208)

Disease

LGG

FDR

5.15E-9

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 C          U   U    GA 5 hsa-miR-185-3p
           UGGUCUCCUU CGG CGGG     
           ACCAGAGGAA GCC GCUC     
target 5 A                   A  3 C8orf31
Start: 843  End: 863
Energy: -33.4 kcal/mol
Align Score: 0.009606
miRNA  3      U                                   5 hsa-miR-185-3p
           CUGG           CUCCUUUC GGUC     GGGGA    
           GACC           GAGGGGAG CCAG     CCCCU    
target 5 C    CCUGCAGCUGU        A    UCUAA     G 3 C8orf31
Start: 291  End: 311
Energy: -31.5 kcal/mol
Align Score: 0.005968
miRNA  3      U                    U             A 5 hsa-miR-185-3p
           CUGG           CUCCUUUCGG         CGGGG    
           GACC           GAGGGAAGCC         GCCCU    
target 5 C    CCUGCAGCUGU          CCGACCUCU     G 3 C8orf31
Start: 291  End: 311
Energy: -32.4 kcal/mol
Align Score: 0.004413
miRNA  3 C          U   U    GA 5 hsa-miR-185-3p
           UGGUCUCCUU CGG CGGG     
           ACCAGAGGAA GCC GCUC     
target 5 A                   A  3 C8orf31
Start: 982  End: 1002
Energy: -33.4 kcal/mol
Align Score: 0.007189
miRNA  3                                U                 A 5 hsa-miR-185-3p
           CUGGUCUCCUU               UCGG             CGGGG    
           GGCUGGGGGAG               AGCC             GCCCC    
target 5 A           AAGUGCACGCUGCCC    UUCAACCUGAACU     C 3 C8orf31
Start: 192  End: 212
Energy: -31.3 kcal/mol
Align Score: 0.009397

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for C8orf31

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-185-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for AKT1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 8q24.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.