Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

12q24.31

lncRNA

LINC01089 ( ENSG00000212694)

miRNA

hsa-miR-185-3p (MIMAT0004611)

mRNA

AKT1 (ENSG00000142208)

Disease

LGG

FDR

3.50E-15

Reported as biomarkers
0

Circulating
0

Drug resistent
2

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'    CUGGUCUCCUUUCGGUCGGGGA 5' hsa-miR-185-3p
                |||||      ||||||| 
target 5' CAUAAGCAGAGAUCA--CAGCCCCA LINC01089
Start: 635  End: 642
Site type: 8mer-1a
Context++ Score: -0.415
miRNA  3'    CUGGUCUCCUUUCGGUCGGGGA 5' hsa-miR-185-3p
                |||||      ||||||| 
target 5' CAUAAGCAGAGAUCA--CAGCCCCA LINC01089
Start: 812  End: 819
Site type: 8mer-1a
Context++ Score: -0.509
miRNA  3'    CUGGUCUCCUUUCGGUCGGGGA 5' hsa-miR-185-3p
                |||||      ||||||| 
target 5' CAUAAGCAGAGAUCA--CAGCCCCA LINC01089
Start: 635  End: 642
Site type: 8mer-1a
Context++ Score: -0.415
miRNA  3'    CUGGUCUCCUUUCGGUCGGGGA 5' hsa-miR-185-3p
                |||||      ||||||| 
target 5' CAUAAGCAGAGAUCA--CAGCCCCA LINC01089
Start: 812  End: 819
Site type: 8mer-1a
Context++ Score: -0.509
RNAbybrid target site prediction
miRNA  3' CU              G     GA 5' hsa-miR-185-3p
            GGUCUC  CUUUCG UCGGG     
            CCGGAG  GGAGGC GGCCC     
target 5'  C      CA      G     G  3' LINC01089
Start: 132  End: 152
Energy: -33.1 kcal/mol
Align Score: 0.002534
miRNA  3'          CUUU             5' hsa-miR-185-3p
           CUGGUCUC    CGGUCGG GGA    
           GGCUGGGG    GCCAGCC CCU    
target 5' G        UUCU       U   G 3' LINC01089
Start: 650  End: 670
Energy: -32.4 kcal/mol
Align Score: 0.008531
miRNA  3'          CUUU             5' hsa-miR-185-3p
           CUGGUCUC    CGGUCGG GGA    
           GGCUGGGG    GCCAGCC CCU    
target 5' G        UUCU       U   G 3' LINC01089
Start: 754  End: 774
Energy: -32.4 kcal/mol
Align Score: 0.007102
miRNA  3'          CUUU             5' hsa-miR-185-3p
           CUGGUCUC    CGGUCGG GGA    
           GGCUGGGG    GCCAGCC CCU    
target 5' G        UUCU       U   G 3' LINC01089
Start: 1035  End: 1055
Energy: -32.4 kcal/mol
Align Score: 0.008866
miRNA  3'     G           U              5' hsa-miR-185-3p
           CUG UCUCCUUUCGG      CGG GGA    
           GGC GGGGGAGGGCC      GCC CCU    
target 5' C   G           CUGGGU   G   A 3' LINC01089
Start: 625  End: 645
Energy: -35.2 kcal/mol
Align Score: 0.003116

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC01089

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-185-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for AKT1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 12q24.31

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.