Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

15q24.1

lncRNA

LOXL1-AS1 ( ENSG00000261801)

miRNA

hsa-miR-326 (MIMAT0000756)

mRNA

PKM (ENSG00000067225)

Disease

LGG

FDR

5.65E-14

Reported as biomarkers
0

Circulating
0

Drug resistent
1

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3      U   U            C 5 hsa-miR-326
           GACC CCU   CCCGGGUCUC    
           CUGG GGA   GGGCCUGGAG    
target 5 U        CUC          C 3 LOXL1-AS1
Start: 75  End: 95
Energy: -32.2 kcal/mol
Align Score: 0.005787
miRNA  3 GA  U                C 5 hsa-miR-326
            CC  CCUUCCCG GGUCUC    
            GG  GGAGGGGC CCGGGG    
target 5  C  CC        G      C 3 LOXL1-AS1
Start: 28  End: 48
Energy: -32.1 kcal/mol
Align Score: 0.004085
miRNA  3 GA                    CC 5 hsa-miR-326
            CCU  CCUUCCC  GGGUCU     
            GGA  GGAGGGG  CCCAGA     
target 5  G   UA       GU      A  3 LOXL1-AS1
Start: 144  End: 164
Energy: -30.9 kcal/mol
Align Score: 0.007543
miRNA  3 GA  UC  UU          C 5 hsa-miR-326
            CC   C  CCCGGGUCUC    
            GG   G  GGGCCCGGAG    
target 5     CCC GG          C 3 LOXL1-AS1
Start: 1  End: 21
Energy: -32.7 kcal/mol
Align Score: 0.00576
miRNA  3 GA   C   UU          C 5 hsa-miR-326
            CCU   C  CCCGGGUCUC    
            GGG   G  GGGCCCGGAG    
target 5      CCC GG          C 3 LOXL1-AS1
Start: 1  End: 21
Energy: -33.3 kcal/mol
Align Score: 0.006565

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LOXL1-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-326

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for PKM

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 15q24.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.