Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

12q24.31

lncRNA

LINC01089 ( ENSG00000212694)

miRNA

hsa-miR-346 (MIMAT0000773)

mRNA

BCL6 (ENSG00000113916)

Disease

LGG

FDR

1.78E-14

Reported as biomarkers
0

Circulating
0

Drug resistent
2

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3            UACG        U 5 hsa-miR-346
           UCUCCGUCCG    CCCGUCUG    
           AGGGGUGGGU    GGGCAGAC    
target 5 C                      U 3 LINC01089
Start: 503  End: 523
Energy: -35.8 kcal/mol
Align Score: 0.003348
miRNA  3 UC    U    A          U    5 hsa-miR-346
            UCCG CCGU  CGC CCGUC GU    
            GGGC GGCA  GCG GGCAG CA    
target 5  A         GG   C     C  A 3 LINC01089
Start: 458  End: 478
Energy: -34.5 kcal/mol
Align Score: 0.006776
miRNA  3            UA    C    GU 5 hsa-miR-346
           UCUCCGUCCG  CGCC GUCU     
           GGAGGCGGGC  GCGG CAGG     
target 5 A          CC    C    U  3 LINC01089
Start: 140  End: 160
Energy: -38.9 kcal/mol
Align Score: 0.000291
miRNA  3            UACG        U 5 hsa-miR-346
           UCUCCGUCCG    CCCGUCUG    
           AGGGGUGGGU    GGGCAGAC    
target 5 C                      U 3 LINC01089
Start: 680  End: 700
Energy: -35.8 kcal/mol
Align Score: 0.002695
miRNA  3            UACG        U 5 hsa-miR-346
           UCUCCGUCCG    CCCGUCUG    
           AGGGGUGGGU    GGGCAGAC    
target 5 C                      U 3 LINC01089
Start: 784  End: 804
Energy: -35.8 kcal/mol
Align Score: 0.002204

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC01089

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-346

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for BCL6

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 12q24.31

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.