Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

5q35.3

lncRNA

PRR7-AS1 ( ENSG00000246334)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

HMGA2 (ENSG00000149948)

Disease

LGG

FDR

4.53E-3

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3                                 CG      5 hsa-miR-370-3p
           UG GUCCA              AGGUGGGGU  UCCG    
           AC CAGGU              UCCACCUCA  GGGC    
target 5 C  A     GUCCUCGCGGCUGC         CA    U 3 PRR7-AS1
Start: 635  End: 655
Energy: -33.4 kcal/mol
Align Score: 0.003982
miRNA  3 U                        U     5 hsa-miR-370-3p
           GGUCCA     AGGUGGGG  UCG CCG    
           CCAGGU     UCCACUUC  GGC GGC    
target 5 C      GAAUG        GA   C   U 3 PRR7-AS1
Start: 197  End: 217
Energy: -34.1 kcal/mol
Align Score: 0.002055
miRNA  3        AA          U    G 5 hsa-miR-370-3p
           UGGUCC  GGUGGGGUCG   CC    
           GCCAGG  CCACCUUAGC   GG    
target 5 A                  CUU  A 3 PRR7-AS1
Start: 334  End: 354
Energy: -33.8 kcal/mol
Align Score: 0.002066
miRNA  3     UCCAA              G 5 hsa-miR-370-3p
           UGG      GGUGGGGUCGUCC    
           GCC      CUACCCCAGCAGG    
target 5 U   UCCCCC             G 3 PRR7-AS1
Start: 148  End: 168
Energy: -35.6 kcal/mol
Align Score: 0.000797

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for PRR7-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for HMGA2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 5q35.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.