Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q37.1

lncRNA

SPATA3-AS1 ( ENSG00000238062)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

TCEAL1 (ENSG00000172465)

Disease

LGG

FDR

2.61E-6

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' ugguccAAGGUGGGGUCGUCCg 5' hsa-miR-370-3p
                |||||  |||||||| 
target 5' gtccacTTCCAAGCCAGCAGGa 3' SPATA3-AS1
Start: 588  End: 609
Energy: -28.21 kcal/mol
Align Score: 164
miRNA  3' ugguccAAGGUGGGGUCGUCCg 5' hsa-miR-370-3p
                |||||  |||||||| 
target 5' gtccacTTCCAAGCCAGCAGGa 3' SPATA3-AS1
Start: 581  End: 602
Energy: -28.21 kcal/mol
Align Score: 164
miRNA  3' ugguccAAGGUGGGGUCGUCCg 5' hsa-miR-370-3p
                |||||  |||||||| 
target 5' gtccacTTCCAAGCCAGCAGGa 3' SPATA3-AS1
Start: 409  End: 430
Energy: -28.21 kcal/mol
Align Score: 164
miRNA  3' ugguccAAGGUGGGGUCGUCCg 5' hsa-miR-370-3p
                |||||  |||||||| 
target 5' gtccacTTCCAAGCCAGCAGGa 3' SPATA3-AS1
Start: 293  End: 314
Energy: -28.21 kcal/mol
Align Score: 164
miRNA  3' ugguccAAGGUGGGGUCGUCCg 5' hsa-miR-370-3p
                |||||  |||||||| 
target 5' gtccacTTCCAAGCCAGCAGGa 3' SPATA3-AS1
Start: 650  End: 671
Energy: -28.21 kcal/mol
Align Score: 164
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3' U     A                       G 5' hsa-miR-370-3p
           GGUCC    AGGUGG      GGUCGUCC    
           CCAGG    UCCACU      CCAGCAGG    
target 5' U     ACCG      UCCAAG        A 3' SPATA3-AS1
Start: 572  End: 592
Energy: -36.6 kcal/mol
Align Score: 0.002102
miRNA  3' U     A                       G 5' hsa-miR-370-3p
           GGUCC    AGGUGG      GGUCGUCC    
           CCAGG    UCCACU      CCAGCAGG    
target 5' U     ACCG      UCCAAG        A 3' SPATA3-AS1
Start: 400  End: 420
Energy: -36.6 kcal/mol
Align Score: 0.001325
miRNA  3' U     A                       G 5' hsa-miR-370-3p
           GGUCC    AGGUGG      GGUCGUCC    
           CCAGG    UCCACU      CCAGCAGG    
target 5' U     ACCG      UCCAAG        A 3' SPATA3-AS1
Start: 284  End: 304
Energy: -36.6 kcal/mol
Align Score: 0.00065
miRNA  3' U     A                       G 5' hsa-miR-370-3p
           GGUCC    AGGUGG      GGUCGUCC    
           CCAGG    UCCACU      CCAGCAGG    
target 5' U     ACCG      UCCAAG        A 3' SPATA3-AS1
Start: 641  End: 661
Energy: -36.6 kcal/mol
Align Score: 0.001299
miRNA  3' U     A                       G 5' hsa-miR-370-3p
           GGUCC    AGGUGG      GGUCGUCC    
           CCAGG    UCCACU      CCAGCAGG    
target 5' U     ACCG      UCCAAG        A 3' SPATA3-AS1
Start: 424  End: 444
Energy: -36.6 kcal/mol
Align Score: 0.000631

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SPATA3-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for TCEAL1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q37.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.