Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

21q22.12

lncRNA

CBR3-AS1 ( ENSG00000236830)

miRNA

hsa-miR-636 (MIMAT0003306)

mRNA

SLC25A5 (ENSG00000005022)

Disease

LGG

FDR

5.05E-4

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 A               C         U    5 hsa-miR-636
           CGC CCGC   CCUG  UC GUUCG GU    
           GCG GGCG   GGAC  AG CAAGC CA    
target 5 A   U    GAU    UU  C        A 3 CBR3-AS1
Start: 538  End: 558
Energy: -30.6 kcal/mol
Align Score: 0.009062
miRNA  3 A               C         U    5 hsa-miR-636
           CGC CCGC   CCUG  UC GUUCG GU    
           GCG GGCG   GGAC  AG CAAGC CA    
target 5 A   U    GAU    UU  C        A 3 CBR3-AS1
Start: 534  End: 554
Energy: -30.6 kcal/mol
Align Score: 0.008988
miRNA  3 A  C    G      C       UGU 5 hsa-miR-636
           CG   CC  CCCUG UCGUUCG      
           GC   GG  GGGAC AGCAGGC      
target 5 A  CCA  AG     A       U   3 CBR3-AS1
Start: 262  End: 282
Energy: -30.5 kcal/mol
Align Score: 0.008012
miRNA  3 A  C    G      C       UGU 5 hsa-miR-636
           CG   CC  CCCUG UCGUUCG      
           GC   GG  GGGAC AGCAGGC      
target 5 A  CCA  AG     A       U   3 CBR3-AS1
Start: 340  End: 360
Energy: -30.5 kcal/mol
Align Score: 0.009483
miRNA  3 A              U         UGU 5 hsa-miR-636
           CG CCCGC CCUGC    CGUUCG      
           GC GGGCG GGAUG    GCAAGU      
target 5 C  A     C     CUCU      C   3 CBR3-AS1
Start: 177  End: 197
Energy: -33.7 kcal/mol
Align Score: 0.002674

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for CBR3-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-636

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for SLC25A5

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 21q22.12

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.