Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

11p15.5

lncRNA

H19 ( ENSG00000130600)

miRNA

hsa-miR-671-5p (MIMAT0003880)

mRNA

FOXM1 (ENSG00000111206)

Disease

LGG

FDR

1.13E-12

Reported as biomarkers
15

Circulating

13

Drug resistent

52

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' gaGGUCGGGGAGGUCCCGAAGga 5' hsa-miR-671-5p
|| |||| ||||||||||
target 5' gcCCCTCCCCACCAGGGCTTCag 3' H19
Start: 2284  End: 2306
Energy: -35.57 kcal/mol
Align Score: 161
miRNA  3' gaGGUCGGGGAGGUCCCGAAGga 5' hsa-miR-671-5p
|| |||| ||||||||||
target 5' gcCCCTCCCCACCAGGGCTTCag 3' H19
Start: 734  End: 756
Energy: -35.57 kcal/mol
Align Score: 161
miRNA  3' gaGGUCGGGGAGGUCCCGAAGga 5' hsa-miR-671-5p
|| |||| ||||||||||
target 5' gcCCCTCCCCACCAGGGCTTCag 3' H19
Start: 1707  End: 1729
Energy: -35.57 kcal/mol
Align Score: 161
miRNA  3' gaGGUCGGGGAGGUCCCGAAGga 5' hsa-miR-671-5p
|| |||| ||||||||||
target 5' gcCCCTCCCCACCAGGGCTTCag 3' H19
Start: 1865  End: 1887
Energy: -35.57 kcal/mol
Align Score: 161
miRNA  3' gaGGUCGGGGAGGUCCCGAAGga 5' hsa-miR-671-5p
|| |||| ||||||||||
target 5' gcCCCTCCCCACCAGGGCTTCag 3' H19
Start: 2217  End: 2239
Energy: -35.57 kcal/mol
Align Score: 161
TargetScan target site prediction
                                           
NA

                         
NA

RNAbybrid target site prediction
miRNA  3'                             GA 5' hsa-miR-671-5p
GAGGU CGGGGAGG UCCCGAAG
CUCUG GCCCCUCC AGGGCUUC
target 5' G U CCACC A 3' H19
Start: 727  End: 747
Energy: -41.1 kcal/mol
Align Score: 0.000284
miRNA  3'                             GA 5' hsa-miR-671-5p
GAGGU CGGGGAGG UCCCGAAG
CUCUG GCCCCUCC AGGGCUUC
target 5' G U CCACC A 3' H19
Start: 1700  End: 1720
Energy: -41.1 kcal/mol
Align Score: 0.000873
miRNA  3'                             GA 5' hsa-miR-671-5p
GAGGU CGGGGAGG UCCCGAAG
CUCUG GCCCCUCC AGGGCUUC
target 5' G U CCACC A 3' H19
Start: 1858  End: 1878
Energy: -41.1 kcal/mol
Align Score: 0.000975
miRNA  3'                             GA 5' hsa-miR-671-5p
GAGGU CGGGGAGG UCCCGAAG
CUCUG GCCCCUCC AGGGCUUC
target 5' G U CCACC A 3' H19
Start: 1759  End: 1779
Energy: -41.1 kcal/mol
Align Score: 0.000889
miRNA  3'                             GA 5' hsa-miR-671-5p
GAGGU CGGGGAGG UCCCGAAG
CUCUG GCCCCUCC AGGGCUUC
target 5' G U CCACC A 3' H19
Start: 1581  End: 1601
Energy: -41.1 kcal/mol
Align Score: 0.000772

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for H19

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-671-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for FOXM1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 11p15.5

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.