Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

14q32.2

lncRNA

MEG3 ( ENSG00000214548)

miRNA

hsa-miR-744-5p (MIMAT0004945)

mRNA

EEF1A2 (ENSG00000101210)

Disease

LGG

FDR

3.04E-10

Reported as biomarkers
9

Circulating
15

Drug resistent
23

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 AC   AA     A        U 5 hsa-miR-744-5p
            GAC  UCGGG UCGGGGCG    
            CUG  AGCCC AGCCCCGU    
target 5  C   CC              C 3 MEG3
Start: 120  End: 140
Energy: -34.2 kcal/mol
Align Score: 0.002433
miRNA  3 A    AAU        AUC         5 hsa-miR-744-5p
           CGAC       CGGG   GGGGCGU    
           GCUG       GCCC   CCCCGCA    
target 5 G    GACCCCU    A         G 3 MEG3
Start: 1414  End: 1434
Energy: -33.7 kcal/mol
Align Score: 0.009004
miRNA  3 A    AAU        AUC         5 hsa-miR-744-5p
           CGAC       CGGG   GGGGCGU    
           GCUG       GCCC   CCCCGCA    
target 5 G    GACCCCU    A         G 3 MEG3
Start: 1630  End: 1650
Energy: -33.7 kcal/mol
Align Score: 0.009996
miRNA  3 A    AAU        AUC         5 hsa-miR-744-5p
           CGAC       CGGG   GGGGCGU    
           GCUG       GCCC   CCCCGCA    
target 5 G    GACCCCU    A         G 3 MEG3
Start: 1266  End: 1286
Energy: -33.7 kcal/mol
Align Score: 0.007885
miRNA  3 A    AAU        AUC         5 hsa-miR-744-5p
           CGAC       CGGG   GGGGCGU    
           GCUG       GCCC   CCCCGCA    
target 5 G    GACCCCU    A         G 3 MEG3
Start: 1510  End: 1530
Energy: -33.7 kcal/mol
Align Score: 0.009498

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for MEG3

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-744-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for EEF1A2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 14q32.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.