Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

3p25.3

lncRNA

THUMPD3-AS1 ( ENSG00000206573)

miRNA

hsa-miR-874-3p (MIMAT0004911)

mRNA

HDAC1 (ENSG00000116478)

Disease

LGG

FDR

1.57E-8

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 AGCC                    5 hsa-miR-874-3p
              AGGGAGCCCGGUCCCGUC    
              UCCUUUGGGCCAGGGUAG    
target 5    U                  U 3 THUMPD3-AS1
Start: 1033  End: 1053
Energy: -42.1 kcal/mol
Align Score: 0.000307
miRNA  3 A   A       A                        C 5 hsa-miR-874-3p
           GCC     GGG GCCCGG            UCCCGU    
           CGG     CCC CGGGUU            AGGGCG    
target 5 G   CUCCG          CCCACCGCCUGA      A 3 THUMPD3-AS1
Start: 7  End: 27
Energy: -32.3 kcal/mol
Align Score: 0.002836
miRNA  3 AG               G    C     5 hsa-miR-874-3p
            CCA   GGGAGC CC GUCC GUC    
            GGU   UCCUUG GG CAGG CAG    
target 5  A   UGC      A  G    A   U 3 THUMPD3-AS1
Start: 121  End: 141
Energy: -30.3 kcal/mol
Align Score: 0.007051
miRNA  3 A                                             5 hsa-miR-874-3p
           GCCAGGGAGC              CCGG        UCCCGUC    
           UGGUUUCUCG              GGUU        AGGGCAG    
target 5 G          AGAUGGAAUCUACU    GCUCCUUG       G 3 THUMPD3-AS1
Start: 181  End: 201
Energy: -32 kcal/mol
Align Score: 0.007856
miRNA  3 A                                             5 hsa-miR-874-3p
           GCCAGGGAGC              CCGG        UCCCGUC    
           UGGUUUCUCG              GGUU        AGGGCAG    
target 5 G          AGAUGGAAUCUACU    GCUCCUUG       G 3 THUMPD3-AS1
Start: 129  End: 149
Energy: -32 kcal/mol
Align Score: 0.005853

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for THUMPD3-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-874-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for HDAC1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 3p25.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.