Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

6q14.3

lncRNA

SNHG5 ( ENSG00000203875)

miRNA

hsa-miR-92b-3p (MIMAT0003218)

mRNA

SMAD7 (ENSG00000101665)

Disease

LGG

FDR

1.02E-3

Reported as biomarkers
2

Circulating
1

Drug resistent
6

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' ccUCCGGCCCUGCUCACGUUAu 5' hsa-miR-92b-3p
            |||| | | :| ||||||| 
target 5' gaAGGCGGCGTTGTGTGCAATt 3' SNHG5
Start: 138  End: 159
Energy: -21.34 kcal/mol
Align Score: 164
miRNA  3' ccUCCGGCCCUGCUCACGUUAu 5' hsa-miR-92b-3p
            |||| | | :| ||||||| 
target 5' gaAGGCGGCGTTGTGTGCAATt 3' SNHG5
Start: 133  End: 154
Energy: -21.34 kcal/mol
Align Score: 164
miRNA  3' ccUCCGGCCCUGCUCACGUUAu 5' hsa-miR-92b-3p
            |||| | | :| ||||||| 
target 5' gaAGGCGGCGTTGTGTGCAATt 3' SNHG5
Start: 422  End: 443
Energy: -21.34 kcal/mol
Align Score: 164
miRNA  3' ccUCCGGCCCUGCUCACGUUAu 5' hsa-miR-92b-3p
            |||| | | :| ||||||| 
target 5' gaAGGCGGCGTTGTGTGCAATt 3' SNHG5
Start: 438  End: 459
Energy: -21.34 kcal/mol
Align Score: 164
miRNA  3' ccUCCGGCCCUGCUCACGUUAu 5' hsa-miR-92b-3p
            |||| | | :| ||||||| 
target 5' gaAGGCGGCGTTGTGTGCAATt 3' SNHG5
Start: 354  End: 375
Energy: -21.34 kcal/mol
Align Score: 164
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3'         CC        G UAU 5' hsa-miR-92b-3p
           CCUCCGG  CUGCUCAC U      
           GGAGGCC  GGCGGGUG A      
target 5' G       AA        G U   3' SNHG5
Start: 332  End: 352
Energy: -32.4 kcal/mol
Align Score: 0.006872
miRNA  3'         CC        G UAU 5' hsa-miR-92b-3p
           CCUCCGG  CUGCUCAC U      
           GGAGGCC  GGCGGGUG A      
target 5' G       AA        G U   3' SNHG5
Start: 413  End: 433
Energy: -32.4 kcal/mol
Align Score: 0.005524
miRNA  3'         CC        G UAU 5' hsa-miR-92b-3p
           CCUCCGG  CUGCUCAC U      
           GGAGGCC  GGCGGGUG A      
target 5' G       AA        G U   3' SNHG5
Start: 325  End: 345
Energy: -32.4 kcal/mol
Align Score: 0.004156
miRNA  3'         CC        G UAU 5' hsa-miR-92b-3p
           CCUCCGG  CUGCUCAC U      
           GGAGGCC  GGCGGGUG A      
target 5' G       AA        G U   3' SNHG5
Start: 249  End: 269
Energy: -32.4 kcal/mol
Align Score: 0.005928
miRNA  3'         CC        G UAU 5' hsa-miR-92b-3p
           CCUCCGG  CUGCUCAC U      
           GGAGGCC  GGCGGGUG A      
target 5' G       AA        G U   3' SNHG5
Start: 464  End: 484
Energy: -32.4 kcal/mol
Align Score: 0.007208

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SNHG5

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-92b-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for SMAD7

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 6q14.3

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.