Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

4q21.22

lncRNA

THAP9-AS1 ( ENSG00000251022)

miRNA

hsa-miR-185-5p (MIMAT0000455)

mRNA

DNMT1 (ENSG00000130816)

Disease

LIHC

FDR

2.27E-6

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'      AGUCCUUGACGGAAAGAGAGGU 5' hsa-miR-185-5p
                             ||||||| 
target 5'     AAUUUGUCAUUAAAUUCUCUCCA THAP9-AS1
Start: 2756  End: 2763
Site type: 8mer-1a
Context++ Score: -0.473
RNAbybrid target site prediction
miRNA  3 A            AAAG          5 hsa-miR-185-5p
           GUCCUU GACGG      AGAGGU    
           CAGGAA CUGCC      UCUCCG    
target 5 C      C     AAUGGG      G 3 THAP9-AS1
Start: 170  End: 190
Energy: -30.1 kcal/mol
Align Score: 0.00881
miRNA  3 A            AAAG          5 hsa-miR-185-5p
           GUCCUU GACGG      AGAGGU    
           CAGGAA CUGCC      UCUCCG    
target 5 C      C     AAUGGG      G 3 THAP9-AS1
Start: 173  End: 193
Energy: -30.1 kcal/mol
Align Score: 0.009858
miRNA  3 A            AAA                   5 hsa-miR-185-5p
           GUCCUU GACGG             GAGAGGU    
           CAGGAA CUGCC             CUCUCCG    
target 5 C      C     AAUGGGUCUCCGG       A 3 THAP9-AS1
Start: 106  End: 126
Energy: -31.1 kcal/mol
Align Score: 0.006891
miRNA  3 A            AAA                   5 hsa-miR-185-5p
           GUCCUU GACGG             GAGAGGU    
           CAGGAA CUGCC             CUCUCCG    
target 5 C      C     AAUGGGUCUCCGG       A 3 THAP9-AS1
Start: 173  End: 193
Energy: -31.1 kcal/mol
Align Score: 0.006577
miRNA  3 A            AAAG          5 hsa-miR-185-5p
           GUCCUU GACGG      AGAGGU    
           CAGGAA CUGCC      UCUCCG    
target 5 C      C     AAUGGG      G 3 THAP9-AS1
Start: 175  End: 195
Energy: -30.1 kcal/mol
Align Score: 0.009523

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for THAP9-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-185-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for DNMT1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 4q21.22

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.