Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

1p22.1

lncRNA

CCDC18-AS1 ( ENSG00000223745)

miRNA

hsa-miR-214-3p (MIMAT0000271)

mRNA

GSR (ENSG00000104687)

Disease

LIHC

FDR

3.38E-5

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
miRNA  3' ugACGGACAGACACGGACGACa 5' hsa-miR-214-3p
            | | | ||||| ||||||| 
target 5' atTTCATTTCTGT-CCTGCTGa 3' CCDC18-AS1
Start: 212  End: 232
Energy: -19.97 kcal/mol
Align Score: 162
miRNA  3' ugACGGACAGACACGGACGACa 5' hsa-miR-214-3p
            | | | ||||| ||||||| 
target 5' atTTCATTTCTGT-CCTGCTGa 3' CCDC18-AS1
Start: 293  End: 313
Energy: -19.97 kcal/mol
Align Score: 162
miRNA  3' ugACGGACAGACACGGACGACa 5' hsa-miR-214-3p
            | | | ||||| ||||||| 
target 5' atTTCATTTCTGT-CCTGCTGa 3' CCDC18-AS1
Start: 940  End: 960
Energy: -19.97 kcal/mol
Align Score: 162
miRNA  3' ugACGGACAGACACGGACGACa 5' hsa-miR-214-3p
            | | | ||||| ||||||| 
target 5' atTTCATTTCTGT-CCTGCTGa 3' CCDC18-AS1
Start: 254  End: 274
Energy: -19.97 kcal/mol
Align Score: 162
miRNA  3' ugACGGACAGACACGGACGACa 5' hsa-miR-214-3p
            | | | ||||| ||||||| 
target 5' atTTCATTTCTGT-CCTGCTGa 3' CCDC18-AS1
Start: 108  End: 128
Energy: -19.97 kcal/mol
Align Score: 162
TargetScan target site prediction
miRNA  3'   UGACGGACAGACACGGACGACA 5' hsa-miR-214-3p
                    ||||| ||||||| 
target 5' AGAUUUCAUUUCUGU-CCUGCUGA CCDC18-AS1
Start: 225  End: 232
Site type: 8mer-1a
Context++ Score: -0.422
miRNA  3'   UGACGGACAGACACGGACGACA 5' hsa-miR-214-3p
                    ||||| ||||||| 
target 5' AGAUUUCAUUUCUGU-CCUGCUGA CCDC18-AS1
Start: 306  End: 313
Site type: 8mer-1a
Context++ Score: -0.422
miRNA  3'   UGACGGACAGACACGGACGACA 5' hsa-miR-214-3p
                    ||||| ||||||| 
target 5' AGAUUUCAUUUCUGU-CCUGCUGA CCDC18-AS1
Start: 953  End: 960
Site type: 8mer-1a
Context++ Score: -0.4
miRNA  3'   UGACGGACAGACACGGACGACA 5' hsa-miR-214-3p
                    ||||| ||||||| 
target 5' AGAUUUCAUUUCUGU-CCUGCUGA CCDC18-AS1
Start: 267  End: 274
Site type: 8mer-1a
Context++ Score: -0.422
miRNA  3'   UGACGGACAGACACGGACGACA 5' hsa-miR-214-3p
                    ||||| ||||||| 
target 5' AGAUUUCAUUUCUGU-CCUGCUGA CCDC18-AS1
Start: 121  End: 128
Site type: 8mer-1a
Context++ Score: -0.438
RNAbybrid target site prediction
miRNA  3' U     A                     A           5' hsa-miR-214-3p
           GACGG      CAGA           C CGGACGACA    
           CUGCU      GUCU           G GCCUGCUGU    
target 5' C     GAUGAA    ACGUUCAUUCA G         G 3' CCDC18-AS1
Start: 225  End: 245
Energy: -29.3 kcal/mol
Align Score: 0.009097
miRNA  3' U     A                     A           5' hsa-miR-214-3p
           GACGG      CAGA           C CGGACGACA    
           CUGCU      GUCU           G GCCUGCUGU    
target 5' C     GAUGAA    ACGUUCAUUCA G         G 3' CCDC18-AS1
Start: 121  End: 141
Energy: -29.3 kcal/mol
Align Score: 0.005976
miRNA  3' U     A                     A           5' hsa-miR-214-3p
           GACGG      CAGA           C CGGACGACA    
           CUGCU      GUCU           G GCCUGCUGU    
target 5' C     GAUGAA    ACGUUCAUUCA G         G 3' CCDC18-AS1
Start: 254  End: 274
Energy: -29.3 kcal/mol
Align Score: 0.009595
miRNA  3' U     A                     A           5' hsa-miR-214-3p
           GACGG      CAGA           C CGGACGACA    
           CUGCU      GUCU           G GCCUGCUGU    
target 5' C     GAUGAA    ACGUUCAUUCA G         G 3' CCDC18-AS1
Start: 77  End: 97
Energy: -29.3 kcal/mol
Align Score: 0.007583
miRNA  3' U     A                     A           5' hsa-miR-214-3p
           GACGG      CAGA           C CGGACGACA    
           CUGCU      GUCU           G GCCUGCUGU    
target 5' C     GAUGAA    ACGUUCAUUCA G         G 3' CCDC18-AS1
Start: 149  End: 169
Energy: -29.3 kcal/mol
Align Score: 0.009484

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for CCDC18-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-214-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for GSR

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 1p22.1

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.