Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

2q31.2

lncRNA

TTN-AS1 ( ENSG00000237298)

miRNA

hsa-miR-34a-5p (MIMAT0000255)

mRNA

GALNT7 (ENSG00000109586)

Disease

PAAD

FDR

1.75E-2

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
miRNA  3'    UGUUGGUCGAUUCUGUGACGGU 5' hsa-miR-34a-5p
                  |||||    ||||||| 
target 5' UGGCUGUACAGCUGA--CACUGCCA TTN-AS1
Start: 765  End: 772
Site type: 8mer-1a
Context++ Score: -0.45
miRNA  3'    UGUUGGUCGAUUCUGUGACGGU 5' hsa-miR-34a-5p
                  |||||    ||||||| 
target 5' UGGCUGUACAGCUGA--CACUGCCA TTN-AS1
Start: 316  End: 323
Site type: 8mer-1a
Context++ Score: -0.437
RNAbybrid target site prediction
miRNA  3 U    GU                U 5 hsa-miR-34a-5p
           GUUG    CGAUUCUGUGACGG    
           UAAC    GCUGAGGCACUGUC    
target 5 C    AUCU              U 3 TTN-AS1
Start: 375  End: 395
Energy: -31.6 kcal/mol
Align Score: 0.005961
miRNA  3 U                               U 5 hsa-miR-34a-5p
           GUUGG        UCGAU   UCUGUGACGG    
           CAACC        GGCUA   AGGCACUGUC    
target 5 C     UCAUUGGU     UGC          U 3 TTN-AS1
Start: 209  End: 229
Energy: -30.2 kcal/mol
Align Score: 0.006925
miRNA  3                           U 5 hsa-miR-34a-5p
           UGUUGG   UCGAUU CUGUGACGG    
           ACAGCC   AGCUGA GGUAUUGCC    
target 5 C      UUU      U         U 3 TTN-AS1
Start: 197  End: 217
Energy: -29.2 kcal/mol
Align Score: 0.005888
miRNA  3    UUG      UU            5 hsa-miR-34a-5p
           UG    GUCGA  CUGUGACGGU    
           GC    CAGCU  GACACUGCCA    
target 5 G  UGUA                 U 3 TTN-AS1
Start: 302  End: 322
Energy: -31.6 kcal/mol
Align Score: 0.008613

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for TTN-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-34a-5p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for GALNT7

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 2q31.2

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.