Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

12q24.31

lncRNA

LINC01089 ( ENSG00000212694)

miRNA

hsa-miR-1291 (MIMAT0005881)

mRNA

ERN1 (ENSG00000178607)

Disease

LUAD

FDR

9.20E-16

Reported as biomarkers
0

Circulating
0

Drug resistent
2

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3      GA     A                         U 5 hsa-miR-1291
           UGAC  CCAGA              GUCAGUCC CGG    
           ACUG  GGUCU              CAGUCAGG GCC    
target 5 C    A      GAGGCUUUUGAGGA        A   C 3 LINC01089
Start: 665  End: 685
Energy: -33.5 kcal/mol
Align Score: 0.007927
miRNA  3 UGA        A    A                     U 5 hsa-miR-1291
             CGACCAGA  GUC               GUCCCGG    
             GCUGGUCU  CAG               CAGGGCU    
target 5   G        GG   GCGGGCCCAGCCGGG       G 3 LINC01089
Start: 28  End: 48
Energy: -35.7 kcal/mol
Align Score: 0.001062
miRNA  3      GA     A                         U 5 hsa-miR-1291
           UGAC  CCAGA              GUCAGUCC CGG    
           ACUG  GGUCU              CAGUCAGG GCC    
target 5 C    A      GAGGCUUUUGAGGA        A   C 3 LINC01089
Start: 842  End: 862
Energy: -33.5 kcal/mol
Align Score: 0.006486
miRNA  3     C    A  A        AG         5 hsa-miR-1291
           UGA GACC GA      GUC  UCCCGGU    
           GCU CUGG CU      CAG  AGGGCCG    
target 5 G        C  GCAGCC   GG       A 3 LINC01089
Start: 511  End: 531
Energy: -31.6 kcal/mol
Align Score: 0.006147
miRNA  3       A    A AA      A           U 5 hsa-miR-1291
           UGACG   CC G     GUC     GUCCCGG    
           ACUGC   GG C     CGG     CGGGGCC    
target 5 A     CCG  C GGAGG   GCGCG       C 3 LINC01089
Start: 249  End: 269
Energy: -31.8 kcal/mol
Align Score: 0.006613

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC01089

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-1291

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for ERN1

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 12q24.31

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.