Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

12q24.31

lncRNA

LINC01089 ( ENSG00000212694)

miRNA

hsa-miR-328-3p (MIMAT0000752)

mRNA

KCNH2 (ENSG00000055118)

Disease

LUAD

FDR

6.69E-18

Reported as biomarkers
0

Circulating
0

Drug resistent
2

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 U   UU       C           5 hsa-miR-328-3p
           GCC  CCCGUCU  UCCCGGUC    
           UGG  GGGCAGA  GGGGCCAG    
target 5 G   GU       CU        U 3 LINC01089
Start: 508  End: 528
Energy: -39.4 kcal/mol
Align Score: 0.0009
miRNA  3 U                       GUC 5 hsa-miR-328-3p
           GCCUUCC CGUCU    CUCCCG      
           UGGAAGG GCAGA    GAGGGU      
target 5 G       A     ACGU      G   3 LINC01089
Start: 824  End: 844
Energy: -34.8 kcal/mol
Align Score: 0.005817
miRNA  3 U                            U            5 hsa-miR-328-3p
           GCCU   UC CCGUC           UC    CCCGGUC    
           CGGA   GG GGCGG           GG    GGGCCGG    
target 5 C    GCA  A     GCCCGCGGCCA  UUCU       A 3 LINC01089
Start: 133  End: 153
Energy: -31.3 kcal/mol
Align Score: 0.005066
miRNA  3 U   UU       C           5 hsa-miR-328-3p
           GCC  CCCGUCU  UCCCGGUC    
           UGG  GGGCAGA  GGGGCCAG    
target 5 G   GU       CU        U 3 LINC01089
Start: 685  End: 705
Energy: -39.4 kcal/mol
Align Score: 0.000707
miRNA  3 U   UU       C           5 hsa-miR-328-3p
           GCC  CCCGUCU  UCCCGGUC    
           UGG  GGGCAGA  GGGGCCAG    
target 5 G   GU       CU        U 3 LINC01089
Start: 789  End: 809
Energy: -39.4 kcal/mol
Align Score: 0.000565

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for LINC01089

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-328-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for KCNH2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 12q24.31

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.