Basic Info

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Basic Information for the CNV-ceRNA event

Cytoband

10p11.23

lncRNA

SVIL-AS1 ( ENSG00000224597)

miRNA

hsa-miR-370-3p (MIMAT0000722)

mRNA

TGFBR2 (ENSG00000163513)

Disease

LUAD

FDR

2.70E-12

Reported as biomarkers
0

Circulating
0

Drug resistent
0

Survival

Binding Info

miRNA Binding site information on lncRNA

miRanda target site prediction
                                           
                       NA                  
                                           
                         
            NA
TargetScan target site prediction
                                           
                       NA                  
                                           
                         
            NA
RNAbybrid target site prediction
miRNA  3 UG          UG               5 hsa-miR-370-3p
            GUCCAA  GG  GGG   UCGUCCG    
            UAGGUU  CC  CUU   GGCGGGC    
target 5  A      CA  UG   CCA       A 3 SVIL-AS1
Start: 310  End: 330
Energy: -32.1 kcal/mol
Align Score: 0.003322
miRNA  3                         UC    5 hsa-miR-370-3p
           UGG  UCCAAGGUG   GGGUCG  CG    
           GCU  AGGUUCCAC   CCUGGU  GC    
target 5 A   CG         CAG      CU  A 3 SVIL-AS1
Start: 281  End: 301
Energy: -31.1 kcal/mol
Align Score: 0.009751
miRNA  3 U     AA    G                     G 5 hsa-miR-370-3p
           GGUCC   GGU GG            GUCGUCC    
           CCGGG   CCA CU            CAGCGGG    
target 5 C     CGG   G  GGGCUCGGAGUG       G 3 SVIL-AS1
Start: 22  End: 42
Energy: -29.3 kcal/mol
Align Score: 0.006409
miRNA  3        A                                           5 hsa-miR-370-3p
           UGGUCC      AGGUGGGG              UCG       UCCG    
           GCCAGG      UCUACCCC              AGC       GGGC    
target 5 A      GGUUUC        CUUCCCUGACUUAC   UGGAACU    U 3 SVIL-AS1
Start: 620  End: 640
Energy: -33.5 kcal/mol
Align Score: 0.007135
miRNA  3        A                                           5 hsa-miR-370-3p
           UGGUCC      AGGUGGGG              UCG       UCCG    
           GCCAGG      UCUACCCC              AGC       GGGC    
target 5 A      GGUUUC        CUUCCCUGACUUAC   UGGAACU    U 3 SVIL-AS1
Start: 870  End: 890
Energy: -33.5 kcal/mol
Align Score: 0.005579

Functions

Dysregulated fucntions of CNV-ceRNA event

Hallmarks

Dysregulated hallmarks of CNV-ceRNA event

Network

Related ceRNA network disturbed by CNV

Survival

Survival status of ceRNA interaction

Samples

Samples with different CNV status

Annotations

External Annotation for SVIL-AS1

LncRNA-associated competing triplets and functions.

Comprehensive experimentally supported associations between lncRNA and human cancer.

An open-source platform for studying the RNA-RNA interactions from CLIP-seq data.

An integrated knowledge database dedicated to non-coding RNAs.

An integrated database of human annotated lncRNA transcripts.

Comprehensive annotations of eukaryotic long non-coding RNAs.



External Annotation for hsa-miR-370-3p

A high quality database of published miRNA sequences and annotation.

A curated miRNA-target database developed by DIANA LAB.

A miRNA-target database by manually filter research articles related to functional studies of miRNAs.

A comprehensive of microRNA diversity, expression profiles, target relationships, and various supporting tools.



External Annotation for TGFBR2

Information on all annotated and predicted human genes.

Gene nomenclature, gene families and associated resources (genomic, proteomic, phenotypic information).

Genome browser for vertebrate genomes.

An annotated collection of all publicly available DNA sequences.



External Annotation for variation: 10p11.23

A comprehensive, authoritative compendium of human genes and genetic phenotypes.

A database of human single nucleotide variations, microsatellites, and small-scale insertions and deletions

The catalogue of somatic mutations in cancer.